Gk - glycerol kinase Gene

Also Known as Gyk; ASTP

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 79223

Summary

Enables histone binding activity. Involved in response to cold; response to ethanol; and response to xenobiotic stimulus. Located in mitochondrion and nucleus. Used to study familial hypercholesterolemia. Human ortholog(s) of this gene implicated in glycerol kinase deficiency. Orthologous to human GK (glycerol kinase). [provided by Alliance of Genome Resources, Apr 2022]

Gk Products (1)

mRNA Protein Name
NM_024381.2 NP_077357.2 glycerol kinase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables histone binding IDA
IDA: Inferred from direct assay
2912694 RGD
Biological Process GO Annotation Evidence References Source
involved in response to ethanol IDA
IDA: Inferred from direct assay
9923724 RGD
involved in response to norepinephrine IEP
IEP: Inferred from expression pattern
12736183 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
16154425 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycerol kinase

  • ATP-stimulated glucocorticoid-receptor translocation promoter

  • ATP-stimulated glucocorticoid-receptor translocaton promoter

  • ATP:glycerol 3-phosphotransferase

  • glycerokinase

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14806B Teneligliptin hydrobromide hydrate 99.97% Unkown
HY-14806A Teneligliptin hydrobromide 99.99% Unkown

Clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-109030 Dorzagliatin Activator 99.89% Phase 4
HY-147254 Cadisegliatin Activator 99.80% Phase 3
HY-13529 Globalagliatin Activator 99.45% Phase 2
HY-160602 CPL207280 Agonist 98.72% Phase 2
HY-144289 BMS-820132 Activator 99.75% Phase 1

Pre-clinical Phase

Bioactive Molecules (47)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12337 GK921 Inhibitor 99.91% Unkown
HY-134816 D-Glucan 96.0% Unkown
HY-13802 SC-514 Inhibitor 99.97% Unkown
HY-153627 GK13S Inhibitor 99.09% Unkown
HY-W040127 Peonidin 3-O-glucoside chloride 98.02% Unkown
HY-10595 RO-28-1675 Activator 99.89% Unkown
HY-12411 AMG-3969 Modulator 99.45% Unkown
HY-122756 N-Palmitoyl-l-leucine Inhibitor 99.98% Unkown
HY-154914 GK16S 98.0% Unkown
HY-100221 AM-2394 Activator 99.30% Unkown
HY-120441 CAY10590 98.0% Unkown
HY-125986 GK187 Inhibitor 98.0% Unkown
HY-12614 AMG-1694 Modulator / Unkown
HY-144287 Glucokinase activator 3 98.36% Unkown
HY-153627A GK13R Inhibitor 98.93% Unkown
HY-109030R Dorzagliatin (Standard) Activator 98.47% Unkown
HY-121070 AZD1092 Activator / Unkown
HY-124487 GK-136901 Inhibitor / Unkown
HY-138990 GK563 Inhibitor / Unkown
HY-154802 TCO-GK-PEG4-NHS ester / Unkown
HY-155328 GK444 Inhibitor / Unkown
HY-155329 GK718 Inhibitor / Unkown
HY-155448 GK56 / Unkown
HY-155449 GK60 / Unkown
HY-155451 GK83 / Unkown
HY-156086 TRK-IN-24 Inhibitor / Unkown
HY-177297 LCZ960 Activator / Unkown
HY-D0573 C.I. Solvent red 197 95.54% Unkown
HY-RS05329 GCK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05330 Gck Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05457 GK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05458 GK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05459 GK5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-120050 GK470 Inhibitor / Unkown
HY-126072 (Rac)-GK563 / Unkown
HY-136631 PF-04279405 Agonist / Unkown
HY-155450 GK81 / Unkown
HY-158792 GK241 / Unkown
HY-173103S FYDPL(Ala-13C3,15N)GK TFA / Unkown
HY-179419 Glucokinase activator 10 Activator / Unkown
HY-180229 GK730 Inhibitor / Unkown
HY-RS17180 Gk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17868 Gk2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18388 Galk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23631 Gk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24337 Gk2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-U00411 PSN-GK1 Activator / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990792 Anti-Mouse CD4 Antibody (GK1.5) Inhibitor 99.16% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gk NCBI NCBI:2710