Vim - vimentin Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81818

Summary

Enables protein kinase binding activity and protein Phosphatase 2A binding activity. Involved in several processes, including decidualization; positive regulation of glial cell proliferation; and response to vitamin D. Located in several cellular components, including axon; cell body; and perinuclear region of cytoplasm. Biomarker of Chagas disease; cerebral infarction; hyperthyroidism; nephrosis; and pulmonary hypertension. Human ortholog(s) of this gene implicated in atherosclerosis; autoimmune disease (multiple); and cataract 30. Orthologous to human VIM (vimentin). [provided by Alliance of Genome Resources, Apr 2022]

Vim Products (1)

mRNA Protein Name
NM_031140.1 NP_112402.1 vimentin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables kinase binding IPI
IPI: Inferred from physical interaction
11082283 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
12639940 RGD
enables protein phosphatase 2A binding IDA
IDA: Inferred from direct assay
10906761 RGD
enables protein tyrosine kinase binding IPI
IPI: Inferred from physical interaction
12700184 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to fibroblast growth factor stimulus IEP
IEP: Inferred from expression pattern
15195687 RGD
involved in decidualization IEP
IEP: Inferred from expression pattern
17653607 RGD
involved in fat cell differentiation IEP
IEP: Inferred from expression pattern
8680470 RGD
involved in positive regulation of glial cell proliferation IMP
IMP: Inferred from mutant phenotype
21250919 RGD
involved in regulation of Schwann cell migration IDA
IDA: Inferred from direct assay
22371530 RGD
involved in regulation of axonogenesis IDA
IDA: Inferred from direct assay
22371530 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
21915674 RGD
involved in response to selenium ion IEP
IEP: Inferred from expression pattern
22002783 RGD
involved in response to vitamin D IEP
IEP: Inferred from expression pattern
18687349 RGD
involved in response to zinc ion IEP
IEP: Inferred from expression pattern
22017769 RGD
involved in skeletal muscle tissue regeneration IEP
IEP: Inferred from expression pattern
18941770 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
18431495 RGD
located in cell body IDA
IDA: Inferred from direct assay
7879923 RGD
located in cell projection IDA
IDA: Inferred from direct assay
7879923 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
21915674 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vimentin

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-109124A Taniborbactam hydrochloride Inhibitor 99.97% Phase 3
HY-109124 Taniborbactam Inhibitor 98.45% Phase 3
HY-148493 MK-3402 Inhibitor 98.18% Phase 1

Pre-clinical Phase

Bioactive Molecules (29)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-151424 Vimentin-IN-1 Inhibitor 99.74% Unkown
HY-124757 FiVe1 Inhibitor 99.90% Unkown
HY-143414 Metallo-β-lactamase-IN-6 Inhibitor / Unkown
HY-143415 Metallo-β-lactamase-IN-7 Inhibitor / Unkown
HY-144100 β-Lactamase-IN-7 Inhibitor / Unkown
HY-144259 Metallo-β-lactamase-IN-2 Inhibitor / Unkown
HY-144261 Metallo-β-lactamase-IN-3 Inhibitor / Unkown
HY-144262 Metallo-β-lactamase-IN-4 Inhibitor / Unkown
HY-144659 Metallo-β-lactamase-IN-5 / Unkown
HY-146165 Metallo-β-lactamase-IN-8 Inhibitor / Unkown
HY-146637 VIM-2-IN-1 Inhibitor / Unkown
HY-155201 YJ182 Inhibitor / Unkown
HY-161310 Metallo-β-lactamase-IN-15 Inhibitor / Unkown
HY-163339 Metallo-β-lactamase-IN-14 Inhibitor / Unkown
HY-168500 Metallo-β-lactamase-IN-16 Inhibitor / Unkown
HY-171112 KSP-1007 Inhibitor / Unkown
HY-174212 MXC-017 Inducer / Unkown
HY-176519 ANT2681 Inhibitor / Unkown
HY-182058 ATM potentiator-1 Inhibitor / Unkown
HY-RS15652 VIM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-122711 3-Cyanochromone Inhibitor / Unkown
HY-128049 ML121 Inhibitor / Unkown
HY-152105 Metallo-β-lactamase-IN-9 Inhibitor / Unkown
HY-173472 MBL-IN-5 Inhibitor / Unkown
HY-175724 MBL-IN-6 Inhibitor / Unkown
HY-178976 YL6113 Inhibitor / Unkown
HY-B0368C epi-D-Captopril Inhibitor / Unkown
HY-RS17324 Vim Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23779 Vim Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vim NCBI NCBI:7431