Glycine-d5
Based on 1 Customer Validation
Glycine-d5 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 4896-77-9
- Formula: C2D5NO2
- Molecular Weight:80.10
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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NMDA Receptor |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 4896-77-9
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Unlabeled Cas 56-40-6
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Appearance Solid
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Molecular Weight 80.10
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Formula C2D5NO2
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Color Light yellow to yellow
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SMILES
[2H]N([2H])C([2H])([2H])C(O[2H])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : ≥ 125 mg/mL (1560.55 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 12.4844 mL | 62.4220 mL | 124.8439 mL | 312.1099 mL |
| 5 mM | 2.4969 mL | 12.4844 mL | 24.9688 mL | 62.4220 mL | |
| 10 mM | 1.2484 mL | 6.2422 mL | 12.4844 mL | 31.2110 mL | |
| 15 mM | 0.8323 mL | 4.1615 mL | 8.3229 mL | 20.8073 mL | |
| 20 mM | 0.6242 mL | 3.1211 mL | 6.2422 mL | 15.6055 mL | |
| 25 mM | 0.4994 mL | 2.4969 mL | 4.9938 mL | 12.4844 mL | |
| 30 mM | 0.4161 mL | 2.0807 mL | 4.1615 mL | 10.4037 mL | |
| 40 mM | 0.3121 mL | 1.5605 mL | 3.1211 mL | 7.8027 mL | |
| 50 mM | 0.2497 mL | 1.2484 mL | 2.4969 mL | 6.2422 mL | |
| 60 mM | 0.2081 mL | 1.0404 mL | 2.0807 mL | 5.2018 mL | |
| 80 mM | 0.1561 mL | 0.7803 mL | 1.5605 mL | 3.9014 mL | |
| 100 mM | 0.1248 mL | 0.6242 mL | 1.2484 mL | 3.1211 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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