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GSK-3174998

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Based on 1 Customer Validation

GSK-3174998 is a humanized IgG1 OX40/TNFRSF4 agonistic monoclonal antibody. GSK-3174998 has the potential for the study of advanced solid tumors. The isotype control for GSK-3174998 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

For research use only. We do not sell to patients.

  • Purity: ≥99.0%
  • CAS No.: 2089398-68-3
  • Molecular Weight:147.197 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for GSK-3174998
  • Experimental Validation Results for GSK-3174998
  • GSK-3174998 Chemical Structure
    GSK-3174998 Chemical Structure
CAS No.: 2089398-68-3
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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GSK-3174998 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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All TNF Receptor Isoforms

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Assay Types
  • 1/16

    Immobilized OX40/TNFRSF4 Protein, Human (HEK293, His, HY-P7394) can bind GSK-3174998. The EC50 for this effect is 5.769 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 Juakat cells with GSK-3174998 (HY-P991052, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • GSK-3174998 Chemical Structure
    1/16
  • GSK-3174998
  • Immobilized OX40/TNFRSF4 Protein, Human (HEK293, His, HY-P7394) can bind GSK-3174998. The EC50 for this effect is 5.769 ng/mL.
  • Flow cytometric analysis of 1X106 Juakat cells with GSK-3174998 (HY-P991052, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).