Hsp90β-IN-2
Hsp90β-IN-2 (Compound 16B) is a selective Hsp90β inhibitor with KDs of 225 nM and 73.32 μM against Hsp90β and Hsp90α. KUNB106 exhibits antiproliferative activity against MDA-MB-231 cells, A549 and SKOV-3 cells. KUNB106 can be used for the study of triple negative breast cancer.
For research use only. We do not sell to patients.
- Formula: C28H36N4O3
- Molecular Weight:476.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HSP90β 225 nM (Kd) |
HSP90α 73.32 μM (Kd) |
Chemical Information
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Molecular Weight 476.61
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Formula C28H36N4O3
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SMILES
CCCC1=CC2=C(C(N3CCC(CC3)O)=CC(N4N=C(C5=C4CC(C)(CC5=O)C)CC)=C2)C(N1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)