M24
M24 is a Mcl-1 selective inhibitor. M24 exhibits good binding affinity against Mcl-1 with Ki value of 0.33 μM. M24 exhibits good anti-proliferative activity and induce apoptosis in HepG2 cells.
For research use only. We do not sell to patients.
- CAS No.: 2761947-05-9
- Formula: C44H40Cl3N5O11S
- Molecular Weight:953.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2761947-05-9
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Molecular Weight 953.24
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Formula C44H40Cl3N5O11S
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SMILES
CC1=CC(OCCOC2=CC=C(C=C2)CN3CC(N(C3=O)CC(NC(C(NS(=O)(C4=CC([N+]([O-])=O)=C(C=C4)Cl)=O)=O)CC5=CC=C(C=C5)OCC6=CC=C(C=C6)Cl)=O)=O)=CC(C)=C1Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)