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Cat. No.: HY-173342

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Neocryptolepine-Cl

(Synonyms: Cryptotackieine-Cl)

Neocryptolepine-Cl (compound Z24) is an inhibitor of Bcthi4 and exhibits excellent antifungal activity against B. cinerea with EC₅₀ value of 0.56 μg/mL.

For research use only. We do not sell to patients.

CAS No.: 1150313-15-7
Formula: C₁₆H₁₁ClN₂
Molecular Weight:266.72

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Neocryptolepine-Cl Chemical Structure

CAS No.: 1150313-15-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Neocryptolepine-Cl (compound Z24) is an inhibitor of Bcthi4 and exhibits excellent antifungal activity against B. cinerea with EC₅₀ value of 0.56 μg/mL^[1].

All Antibiotic Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
MRC5	IC₅₀	>64 μM Compound: 10c	Cytotoxicity against human MRC5 SV2 cells after 72 hrs by resazurin-based fluorometric assay Cytotoxicity against human MRC5 SV2 cells after 72 hrs by resazurin-based fluorometric assay	[PMID: 19364118]

Chemical Information

CAS No. 1150313-15-7
Molecular Weight 266.72
Formula C₁₆H₁₁ClN₂
SMILES

ClC(C=C1)=CC2=C1C3=CC4=CC=CC=C4N(C)C3=N2
Synonyms

Cryptotackieine-Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wen-Bin Zhao, et al. Indoloquinoline alkaloid neocryptolepine derivative inhibits Botrytis cinerea by targeting thiamine thiazole synthase. Sci Adv. 2025 Mar 14;11(11):eadq5329. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Neocryptolepine-Cl

All Antibiotic Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Neocryptolepine-Cl Related Classifications

HY-173342 Related Classifications