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20-HEPE

20-HEPE is a metabolite of eicosapentaenoic acid formed by ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B. At 10 μM, it activates peroxisome proliferator-activated receptor α (PPARα) in COS-7 cells expressing a luciferase reporter gene. 20-HEPE also activates mouse transient receptor potential vanilloid receptor 1 (mTRPV1) in vitro but lacks analgesic activity in rats.

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  • CAS 番号: 116477-57-7
  • 分子式: C20H30O3
  • 分子量:318.45
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • 20-HEPE Chemical Structure
    20-HEPE 構造式
CAS 番号: 116477-57-7
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    20-HEPE Chemical Structure
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  • 20-HEPE