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製品番号: HY-184843

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4-Methoxywarfarin

4-Methoxywarfarin (compound 15) is a racemic inhibitor of cytochrome P450 2C9 (CYP2C9). 4-Methoxywarfarin inhibits CYP2C9-catalyzed S-warfarin 7-hydroxylation with a K_i of 11 μM. 4-Methoxywarfarin is applicable to studies related to CYP2C9 inhibition, warfarin metabolism, and the structure-activity relationship of CYP2C9 inhibitors.

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CAS 番号: 38063-51-3
分子式: C₂₀H₁₈O₄
分子量:322.35

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

4-Methoxywarfarin 構造式

CAS 番号: 38063-51-3

価格（税別）

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IC₅₀ & Target

^[1]

CYP2C9

11 μM (Ki)

Cytochrome P450 アイソフォーム固有の製品をすべて表示 :

体外実験

4-Methoxywarfarin (compound 15) inhibits CYP2C9-catalyzed S-warfarin 7-hydroxylation, with a measured K_i of 11 μM, which is consistent with the K_i of 11 μM predicted by its CoMFA model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 38063-51-3
分子量 322.35
分子式 C₂₀H₁₈O₄
SMILES

O=C1OC2=C(C(OC)=C1C(CC(C)=O)C3=CC=CC=C3)C=CC=C2
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Zhou SF, et al. Substrates, inducers, inhibitors and structure-activity relationships of human cytochrome P450 2C9 and implications in drug development. Current Medicinal Chemistry. 2009;16(27):3480-3675.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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