8CN
8CN, a 2-amino-thiophene derivative, has anti-leishmanial activity. 8CN can be used in research of Leishmaniasis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 40106-14-7
- 分子式: C11H14N2S
- 分子量:206.31
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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Leishmania |
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| J774.A1 | CC50 |
43.9 μM
Compound: 8CN
|
Cytotoxicity against mouse J774.A1 cells incubated for 72 hrs by MTT colorimetric assay
Cytotoxicity against mouse J774.A1 cells incubated for 72 hrs by MTT colorimetric assay
|
[PMID: 36848847] |
8CN (72 h) has anti-leishmanial activity against the two evolutionary forms of Leishmania amazonensis (amastigotes and promastigotes) with IC50 values of 9.8 and 1.2 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 40106-14-7
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分子量 206.31
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分子式 C11H14N2S
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SMILES
C1CCCC2=C(CC1)C(=C(N)S2)C#N
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)