BPH-715
Based on 1 Customer Validation
BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth, with an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.91%
- CAS 番号: 1059677-23-4
- 分子式: C17H31NO7P2
- 分子量:423.38
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
10 μM
Compound: BPH-715
|
Antimalarial activity against Plasmodium berghei NK65 infected in human HepG2 cells after 48 hrs by RT-PCR
Antimalarial activity against Plasmodium berghei NK65 infected in human HepG2 cells after 48 hrs by RT-PCR
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[PMID: 20457823] |
| MDA-MB-231 | IC50 |
100 nM
Compound: BPH-715
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Growth inhibition of human MDA-MB-231 cells
Growth inhibition of human MDA-MB-231 cells
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[PMID: 21780776] |
化学情報
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CAS 番号 1059677-23-4
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性状 Solid
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分子量 423.38
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分子式 C17H31NO7P2
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Color White to off-white
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SMILES
CCCCCCCCCCOC1=C[N+](CC(P(O)(O)=O)P(O)([O-])=O)=CC=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
0.5 M NaOH : 80 mg/mL (188.96 mM; ultrasonic and adjust pH to 11 with NaOH)
DMSO : 5 mg/mL (11.81 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (265 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / 0.5 M NaOH | 1 mM | 2.3619 mL | 11.8097 mL | 23.6194 mL | 59.0486 mL |
| 5 mM | 0.4724 mL | 2.3619 mL | 4.7239 mL | 11.8097 mL | |
| 10 mM | 0.2362 mL | 1.1810 mL | 2.3619 mL | 5.9049 mL | |
| 0.5 M NaOH | 15 mM | 0.1575 mL | 0.7873 mL | 1.5746 mL | 3.9366 mL |
| 20 mM | 0.1181 mL | 0.5905 mL | 1.1810 mL | 2.9524 mL | |
| 25 mM | 0.0945 mL | 0.4724 mL | 0.9448 mL | 2.3619 mL | |
| 30 mM | 0.0787 mL | 0.3937 mL | 0.7873 mL | 1.9683 mL | |
| 40 mM | 0.0590 mL | 0.2952 mL | 0.5905 mL | 1.4762 mL | |
| 50 mM | 0.0472 mL | 0.2362 mL | 0.4724 mL | 1.1810 mL | |
| 60 mM | 0.0394 mL | 0.1968 mL | 0.3937 mL | 0.9841 mL | |
| 80 mM | 0.0295 mL | 0.1476 mL | 0.2952 mL | 0.7381 mL | |
| 100 mM | 0.0236 mL | 0.1181 mL | 0.2362 mL | 0.5905 mL |
BPH-715 関連分類
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