Butylparaben
Based on 2 publication(s) in Google Scholar
Butylparaben is an organic compound that has proven to be a very successful antimicrobial preservative in cosmetics, can also be used in active molecule suspensions, and as a food flavoring additive.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.45%
- CAS 番号: 94-26-8
- 分子式: C11H14O3
- 分子量:194.23
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-N2026
PropylparabenBacterial Inhibitor -
HY-N0349
Methyl parabenBacterial Inhibitor -
HY-B1431R
Butylparaben (Standard)Bacterial Inhibitor -
HY-B0934
EthylparabenAntifungal Agent -
HY-B1431B
Butylparaben, ≥99%Preservative -
HY-B1945
DEHPEndogenous Metabolite -
HY-B0934R
Ethylparaben (Standard)Antifungal Agent -
HY-Y0304
Dibutyl phthalatePlasticizer -
HY-Y0284
Diethyl phthalatePlasticizer -
HY-N0349R
Methyl paraben (Standard)Bacterial Inhibitor -
HY-B1945R
DEHP (Standard)Endogenous Metabolite -
![Benzo[a]pyrene](https://file.medchemexpress.com/product_pic/hy-107377.gif)
HY-107377
Benzo[a]pyreneNoxious Pollutant
MedChemExpress（MCE）の使用を引用している文献 Butylparaben
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MoreEndogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
Butylparaben (0-500 μM, 44 h) inhibits orcine fertilization, cleavage, and blastocyst formation rates[2].
Butylparaben induces DNA Damage, apoptosis, and autophagy in porcine oocytes[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 94-26-8
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性状 Solid
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分子量 194.23
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分子式 C11H14O3
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Color White to off-white
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SMILES
O=C(OCCCC)C1=CC=C(O)C=C1
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別名
Butyl parahydroxybenzoate; Butyl paraben; Butyl 4-hydroxybenzoate
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (2)
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Journal Impact Factor
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Most Recent
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J Hazard Mater
Butylparaben induced zebrafish (Danio rerio) kidney injury by down-regulating the PI3K-AKT pathway. [Abstract]2024 May 15:470:134129. PMID: 38565019 -
溶剤 & 溶解度
体外:
DMSO : ≥ 2.0 mg/mL (10.30 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
純度とドキュメンテーション
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データシート (270 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Bae JS, et al. Thirteen-week subcutaneous repeated dose toxicity study of butylparaben and its toxicokinetics in rats. Arch Toxicol. 2021 Jun;95(6):2037-2050. [Content Brief]
[2]. Jeong PS, et al. Butylparaben Is Toxic to Porcine Oocyte Maturation and Subsequent Embryonic Development Following In Vitro Fertilization. Int J Mol Sci. 2020 May 24;21(10):3692. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1485 mL | 25.7427 mL | 51.4854 mL | 128.7134 mL |
| 5 mM | 1.0297 mL | 5.1485 mL | 10.2971 mL | 25.7427 mL | |
| 10 mM | 0.5149 mL | 2.5743 mL | 5.1485 mL | 12.8713 mL |
Butylparaben 関連分類
HY-B1431 関連分類
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