Brassicasterol (Standard)
Brassicasterol (Standard) is the analytical standard of Brassicasterol (HY-113289). This product is intended for research and analytical applications. Brassicasterol is a metabolite of Ergosterol and has cardiovascular protective effects. Brassicasterol exerts anticancer effects in prostate cancer through dual targeting of AKT and androgen receptor signaling pathways. Brassicasterol inhibits HSV-1 (IC50=1.2 μM) and Mycobacterium tuberculosis. Brassicasterol also inhibits sterol δ 24-reductase, slowing the progression of atherosclerosis. Brassicasterol is also a cerebrospinal fluid biomarker for Alzheimer's disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 474-67-9
- 分子式: C28H46O
- 分子量:398.66
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
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HY-113289
BrassicasterolAndrogen/HSV-1 Inhibitor -
HY-N2335
CoumestrolEstrogen Receptor/ERR Inhibitor -
HY-B0589S
Atorvastatin-d5 hemicalciumStable Isotope -
HY-N2335R
Coumestrol (Standard)Estrogen Receptor/ERR Inhibitor -
HY-165131
Δ7-AvenasterolProstaglandin E2 Receptor/COX-2 Binder -
HY-147087
YSK 05Cationic Lipid -
HY-B0602
Desvenlafaxine5-HT/Norepinephrine Reuptake Inhibitor -
HY-N1082
VisnaginAnti-inflammatory Drug -
HY-W004486
Gallic aldehydeHSV-1 Inhibitor -
HY-N1082R
Visnagin (Standard)Anti-inflammatory Drug -
HY-B0602R
Desvenlafaxine (Standard)5-HT/Norepinephrine Reuptake Inhibitor
Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 474-67-9
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分子量 398.66
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分子式 C28H46O
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SMILES
C[C@H](C(C)C)/C=C/[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Yasuharu Yazawa, et al. Inhibitory effect of ergosterol on bladder carcinogenesis is due to androgen signaling inhibition by brassicasterol, a metabolite of ergosterol. J Nat Med. 2020 Sep;74(4):680-688. [Content Brief]
[2]. Sherif T S Hassan. Brassicasterol with Dual Anti-Infective Properties against HSV-1 and Mycobacterium tuberculosis, and Cardiovascular Protective Effect: Nonclinical In Vitro and In Silico Assessments. Biomedicines. 2020 May 24;8(5):132. [Content Brief]
[3]. Yinzhu Xu, et al. Brassicasterol from Edible Aquacultural Hippocampus abdominalis Exerts an Anti-Cancer Effect by Dual-Targeting AKT and AR Signaling in Prostate Cancer. Biomedicines. 2020 Sep 22;8(9):370. [Content Brief]
[4]. Vanmierlo T, et al. The plant sterol brassicasterol as additional CSF biomarker in Alzheimer's disease. Acta Psychiatr Scand. 2011 Sep;124(3):184-92. [Content Brief]
[5]. Fernández C, et al. Inhibition of cholesterol biosynthesis by Delta22-unsaturated phytosterols via competitive inhibition of sterol Delta24-reductase in mammalian cells. Biochem J. 2002 Aug 15;366(Pt 1):109-19. [Content Brief]
[6]. Tansley G, et al. Sterol lipid metabolism in down syndrome revisited: down syndrome is associated with a selective reduction in serum brassicasterol levels. Curr Gerontol Geriatr Res. 2012;2012:179318. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Brassicasterol (Standard) 関連分類
HY-113289R 関連分類
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