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United States

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製品番号: HY-107331

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Chlorproguanil

Chlorproguanil is an antifolate with an IC₅₀ of 4.68 μM against Plasmodium falciparum female gamete formation. Chlorproguanil can be used for the research of malaria.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 537-21-3
分子式: C₁₁H₁₅Cl₂N₅
分子量:288.18

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Chlorproguanil 構造式

CAS 番号: 537-21-3

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Chlorproguanil is an antifolate with an IC₅₀ of 4.68 μM against Plasmodium falciparum female gamete formation. Chlorproguanil can be used for the research of malaria^[1].

Parasite アイソフォーム固有の製品をすべて表示 :

体外実験

Chlorproguanil (0-25 μM; 48 h) inhibits P. falciparum stage V female gametocyte activation with a mean IC₅₀ of 4.68 μM following 48 h incubation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

臨床実験

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991			2011-05	PHASE1

化学情報

CAS 番号 537-21-3
分子量 288.18
分子式 C₁₁H₁₅Cl₂N₅
SMILES

ClC1=CC=C(C=C1Cl)NC(=N)NC(=N)NC(C)C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Miguel-Blanco C, et al. Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation. Antimicrob Agents Chemother. 2015;59(6):3298-305. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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