Creosol-d4
Creosol-d4 (2-Methoxy-4-methylphenol-d4) is the deuterium labeled Creosol (HY-W040971). Creosol (2-Methoxy-4-methylphenol) is an endogenous metabolite that acts as an important chemical intermediate and potential biofuel mainly derived from lignocellulosic biomass. Creosol is blood brain barrier penetrable.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 20189-08-6
- 分子式: C8H6D4O2
- 分子量:142.19
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 20189-08-6
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非標識Cas 93-51-6
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分子量 142.19
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分子式 C8H6D4O2
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SMILES
COC1=C(C([2H])=C([2H])C(C)=C1[2H])O[2H]
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別名
2-Methoxy-4-methylphenol-d4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[2]. Meylemans HA, Groshens TJ, Harvey BG. Synthesis of renewable bisphenols from creosol. ChemSusChem. 2012 Jan 9;5(1):206-10. [Content Brief]
[4]. Lee JH, et al., Fucoidan Rescues p-Cresol-Induced Cellular Senescence in Mesenchymal Stem Cells via FAK-Akt-TWIST Axis. Mar Drugs. 2018 Apr 6;16(4):121. [Content Brief]
[5]. Tevzadze G, et al. Gut neurotoxin p-cresol induces brain-derived neurotrophic factor secretion and increases the expression of neurofilament subunits in PC-12 cells. AIMS Neurosci. 2021 Dec 23;9(1):12-23. [Content Brief]
[6]. Bermudez-Martin P, et al., The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota. Microbiome. 2021 Jul 8;9(1):157. [Content Brief]
[7]. Chang MC, et al., Antiplatelet effect by p-cresol, a uremic and environmental toxicant, is related to inhibition of reactive oxygen species, ERK/p38 signaling and thromboxane A2 production. Atherosclerosis. 2011 Dec;219(2):559-65. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Creosol-d4 関連分類
HY-W040971S 関連分類
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