CUMI-101
CUMI-101 (compound 8) is a 5-HT1AR agonist (Ki=0.15 nM) with an EC50 of 0.1 nM in the [35S]GTPγS binding assay. CUMI-101 can be used in the research of neurological diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 179756-61-7
- 分子式: C19H27N5O3
- 分子量:373.45
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
5-HT Receptor アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
0.1 nM
Compound: 8, CUMI-101
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Agonist activity at human 5HT1AR expressed in CHO cells assessed as increase in [35S]GTPgammaS binding by liquid scintillation spectrometry
Agonist activity at human 5HT1AR expressed in CHO cells assessed as increase in [35S]GTPgammaS binding by liquid scintillation spectrometry
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[PMID: 25182564] |
| CHO | EC50 |
0.1 nM
Compound: CUMI-101
|
Partial agonist activity at human 5HT1A receptor expressed in CHO cells assessed as increase in [35S]GTPgammaS binding
Partial agonist activity at human 5HT1A receptor expressed in CHO cells assessed as increase in [35S]GTPgammaS binding
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[PMID: 23816046] |
化学情報
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CAS 番号 179756-61-7
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分子量 373.45
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分子式 C19H27N5O3
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SMILES
O=C(N(N=CC1=O)CCCCN2CCN(CC2)C3=CC=CC=C3OC)N1C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CUMI-101 関連分類
HY-116065 関連分類
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