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Donzakimig

(別名: UCB-1381)
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Based on 1 Customer Validation

Donzakimig is a trispecific anti-IL-13/IL-22/HSA antibody. Donzakimig adopts a Fab-scFv-scFv structural format (without an Fc region), in which the Fab domain is linked to the scFv domains via a S (G4S)2 linker. Donzakimig binds to and inhibits the activities of IL-13 and IL-22, thereby blocking the signal transduction of these two cytokines. Donzakimig can extend its serum half-life by binding to human serum albumin, enhancing its in vivo stability and achieving long-acting efficacy. Donzakimig can be used in research on moderate-to-severe atopic dermatitis, moderate-to-severe asthma (especially eosinophilic type), psoriasis, inflammatory bowel disease, and other conditions.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度: 98.67%
  • CAS 番号: 2765066-99-5
  • 分子量:101.048 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Donzakimig
  • Experimental Validation Results for Donzakimig
  • Experimental Validation Results for Donzakimig
  • Experimental Validation Results for Donzakimig
  • Donzakimig Chemical Structure
    Donzakimig 構造式
CAS 番号: 2765066-99-5
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Fab-G1_kappa-scFv-heavy-kappa

  • 1/16

    Immobilized Human IL-22 Protein, His Tag can bind Donzakimig. The EC50 for this effect is 232 ng/mL.

  • 1/16

    Immobilized Human ALB-His-Q Tag can bind Donzakimig. The EC50 for this effect is 145.8 ng/mL.

  • 1/16

    Immobilized Human IL-13 Protein, His Tag can bind Donzakimig. The EC50 for this effect is 287.2 ng/mL.

  • Donzakimig Chemical Structure
    1/16
  • Donzakimig
  • Immobilized Human IL-22 Protein, His Tag can bind Donzakimig. The EC50 for this effect is 232 ng/mL.
  • Immobilized Human ALB-His-Q Tag can bind Donzakimig. The EC50 for this effect is 145.8 ng/mL.
  • Immobilized Human IL-13 Protein, His Tag can bind Donzakimig. The EC50 for this effect is 287.2 ng/mL.
  • Fab-G1_kappa-scFv-heavy-kappa