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United States

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製品番号: HY-19501

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DPC-168

DPC-168 is an orally effective CCR3 antagonist (IC₅₀ = 41 nM). DPC-168 exhibits a significant ability to inhibit eosinophil chemotaxis and pulmonary inflammation. DPC-168 can be used for research on airway inflammation.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 275810-55-4
分子式: C₂₈H₃₆FN₃O₂
分子量:465.60

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

DPC-168 構造式

CAS 番号: 275810-55-4

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

CCR アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	IC₅₀	2 nM Compound: 1, DPC168	Displacement of [125I]eotaxin from human CCR3 expressed in CHO cells after 30 mins Displacement of [125I]eotaxin from human CCR3 expressed in CHO cells after 30 mins	[PMID: 17418570]
CHO	IC₅₀	2 nM Compound: 2a	Displacement of [125I]eotaxin from human CCR3 receptor expressed in CHO cells Displacement of [125I]eotaxin from human CCR3 receptor expressed in CHO cells	[PMID: 18096386]
CHO	IC₅₀	2 nM Compound: 32	Inhibition of [125I]eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cells Inhibition of [125I]eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cells	[PMID: 15771462]
CHO	IC₅₀	54 nM Compound: 1, DPC168	Displacement of [125I]eotaxin from BALB/c mouse CCR3 expressed in CHO cells after 30 mins Displacement of [125I]eotaxin from BALB/c mouse CCR3 expressed in CHO cells after 30 mins	[PMID: 17418570]

化学情報

CAS 番号 275810-55-4
分子量 465.60
分子式 C₂₈H₃₆FN₃O₂
SMILES

O=C(N[C@H]1[C@H](CN2C[C@H](CC3=CC=C(F)C=C3)CCC2)CCCC1)NC4=CC=CC(C(C)=O)=C4
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (270 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. D'Elios M M, et al. Interfering with chemokines and chemokine receptors as potential new therapeutic strategies[J]. Expert Opinion on Therapeutic Patents, 2008, 18(3): 309-325.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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