Drupacine
Drupacine is a natural product, that can be isolated from Cephalotaxus harringtonia. Drupacine shows nematotoxicity and anticancer activity.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 49686-57-9
- 分子式: C18H21NO5
- 分子量:331.36
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
Drupacine shows cytotoxic effect on HCT-116, with IC50 of 16.20 ± 3.44 μM[1].
Drupacine shows cytotoxic effect for Bursaphelenchus xylophilus with ED50 of 27.1?μg/mL, and for Meloidogyne incognita with ED50 of 76.3?μg/mL, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 49686-57-9
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分子量 331.36
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分子式 C18H21NO5
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SMILES
O[C@H]1[C@]2([H])[C@]34C[C@]1(O[C@](CN3CCC4)([H])C5=CC(OCO6)=C6C=C25)OC
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Li Y, et al. Preparation of Stereo-Divergent Compounds from the Natural Product Drupacine Based on Complexity-to-Diversity Strategy. Chem Biodivers. 2023 Jun;20(6):e202300263. [Content Brief]
[2]. Wen Y, et al. Nematotoxicity of drupacine and a Cephalotaxus alkaloid preparation against the plant-parasitic nematodes Meloidogyne incognita and Bursaphelenchus xylophilus. Pest Manag Sci. 2013 Sep;69(9):1026-33. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Drupacine 関連分類
HY-N3786 関連分類
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