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EZH2-IN-23

EZH2-IN-23 (Compound 25) is an EZH2 inhibitor that exhibits potent enzymatic inhibition of the PRC2 complex (EZH2, EED, SUZ12, AEBP2, RbAp48) with a biochemical IC50 of 0.8 nM. EZH2-IN-23 inhibits H3K27 trimethylation in cellular assays, showing an IC50 of 40 nM. EZH2-IN-23 displays good rat PKproperties with 100 % oral bioavailability.

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  • CAS 番号: 3095068-20-2
  • 分子式: C29H35ClN4O2S
  • 分子量:539.13
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • EZH2-IN-23 Chemical Structure
    EZH2-IN-23 構造式
CAS 番号: 3095068-20-2
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  • EZH2-IN-23 Chemical Structure
    EZH2-IN-23 Chemical Structure
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  • EZH2-IN-23