BIRC5 - baculoviral IAP repeat containing 5 Gene

Also Known as API4; EPR-1

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 332

About BIRC5

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:78,214,253-78,225,635 (from NCBI)

This gene has 11 transcripts (splice variants), 218 orthologues and 7 paralogues. Biased expression in bone marrow (RPKM 13.2), testis (RPKM 10.8) and 12 other tissues.

Summary

This gene is a member of the inhibitor of Apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

BIRC5 Products (6)

mRNA Protein Name
NM_001168.3 NP_001159.2 baculoviral IAP repeat-containing protein 5 isoform 1
NM_001012270.2 NP_001012270.1 baculoviral IAP repeat-containing protein 5 isoform 2
NM_001012271.2 NP_001012271.1 baculoviral IAP repeat-containing protein 5 isoform 3
NM_001012270.2 NP_001012270.1 baculoviral IAP repeat-containing protein 5 isoform 2
NM_001012271.2 NP_001012271.1 baculoviral IAP repeat-containing protein 5 isoform 3
NM_001168.3 NP_001159.2 baculoviral IAP repeat-containing protein 5 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
9859993 GOA
enables enzyme binding IPI
IPI: Inferred from physical interaction
16322459 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
16291752 GOA
enables microtubule binding IDA
IDA: Inferred from direct assay
9859993 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
11069302 GOA
enables protein heterodimerization activity IDA
IDA: Inferred from direct assay
16291752 GOA
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
10876248 GOA
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
16291752 GOA
enables protein-folding chaperone binding IPI
IPI: Inferred from physical interaction
18086682 GOA
enables small GTPase binding IPI
IPI: Inferred from physical interaction
18591255 GOA
enables tubulin binding IDA
IDA: Inferred from direct assay
9859993 GOA
enables zinc ion binding IDA
IDA: Inferred from direct assay
10876248 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in G2/M transition of mitotic cell cycle IDA
IDA: Inferred from direct assay
9859993 GOA
involved in cell division IMP
IMP: Inferred from mutant phenotype
12805209 GOA
involved in establishment of chromosome localization IMP
IMP: Inferred from mutant phenotype
12805209 GOA
involved in mitotic cytokinesis IMP
IMP: Inferred from mutant phenotype
12805209 GOA
involved in mitotic spindle assembly checkpoint signaling IMP
IMP: Inferred from mutant phenotype
12805209 GOA
involved in negative regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
20826784 GOA
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
9256286 GOA
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
21536684 GOA
involved in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
IDA: Inferred from direct assay
12773388 GOA
involved in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
9859993 GOA
involved in positive regulation of exit from mitosis IMP
IMP: Inferred from mutant phenotype
12805209 GOA
involved in positive regulation of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
16291752 GOA
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
21252625 GOA
involved in protein-containing complex localization IMP
IMP: Inferred from mutant phenotype
16239925 GOA
involved in sensory perception of sound IEP
IEP: Inferred from expression pattern
20627126 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in centriole IDA
IDA: Inferred from direct assay
9859993 GOA
part of chromosome passenger complex IPI
IPI: Inferred from physical interaction
15260989 GOA
located in chromosome, centromeric region IDA
IDA: Inferred from direct assay
11084331 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
9256286 GOA
located in cytoplasmic microtubule IDA
IDA: Inferred from direct assay
9859993 GOA
located in cytosol IDA
IDA: Inferred from direct assay
12773388 GOA
located in interphase microtubule organizing center IDA
IDA: Inferred from direct assay
9859993 GOA
located in kinetochore IDA
IDA: Inferred from direct assay
15665297 GOA
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
9859993 GOA
located in midbody IDA
IDA: Inferred from direct assay
9859993 GOA
located in nuclear chromosome IDA
IDA: Inferred from direct assay
16322459 GOA
located in nucleus IDA
IDA: Inferred from direct assay
15665297 GOA
part of protein-containing complex IDA
IDA: Inferred from direct assay
12773388 GOA
located in spindle microtubule IDA
IDA: Inferred from direct assay
9859993 GOA
part of survivin complex IPI
IPI: Inferred from physical interaction
10949038 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BIRC5 Protein Structure

BIR

BIR: pfam00653 (17 - 86)

  • 0
  • 100
  • 142 a.a.
Protein Preferred Names Protein Names

baculoviral IAP repeat-containing protein 5

  • apoptosis inhibitor 4

BIRC5 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
BIRC5 O15392 APP Homo sapiens P05067-2
Validated Y2H
32814053
Intra
BIRC5 O15392 APP Homo sapiens P05067-2
Y2H Array
32814053
Intra
BIRC5 O15392 APP Homo sapiens P05067-2
Y2H Pooling
32814053
Intra
BIRC5 O15392 APBB2 Homo sapiens Q92870-2
Validated Y2H
32814053
Intra
BIRC5 O15392 APBB2 Homo sapiens Q92870-2
Y2H Array
32814053
Intra
BIRC5 O15392 APBB2 Homo sapiens Q92870-2
Y2H Pooling
32814053
Intra
BIRC5 O15392 DCTN1 Homo sapiens Q14203-5
Y2H Pooling
32814053
Intra
BIRC5 O15392 DCTN1 Homo sapiens Q14203-5
Validated Y2H
32814053
Intra
BIRC5 O15392 DCTN1 Homo sapiens Q14203-5
Y2H Array
32814053
Intra
BIRC5 O15392 PINK1 Homo sapiens Q9BXM7
Y2H Array
32814053
Intra
BIRC5 O15392 PINK1 Homo sapiens Q9BXM7
Validated Y2H
32814053
Intra
BIRC5 O15392 PINK1 Homo sapiens Q9BXM7
Y2H Pooling
32814053
Intra
BIRC5 O15392 RAN Homo sapiens P62826
Anti Bait CoIP
23251006
Intra
BIRC5 O15392 RAN Homo sapiens P62826
Pull Down
23251006
Intra
BIRC5 O15392 RAN Homo sapiens P62826
ELISA
23251006
Intra
BIRC5 O15392 RAN Homo sapiens P62826
PLA
23251006
Intra
BIRC5 O15392 INCENP Homo sapiens Q9NQS7
X-Ray Diffraction
17956729
Intra
BIRC5 O15392 INCENP Homo sapiens Q9NQS7
GMS
17956729
Intra
BIRC5 O15392 INCENP Homo sapiens Q9NQS7
Anti Tag CoIP
33961781
Intra
BIRC5 O15392 INCENP Homo sapiens Q9NQS7
PLA
21051298
Intra
BIRC5 O15392 INCENP Homo sapiens Q9NQS7
Anti Bait CoIP
21225229
Intra
BIRC5 O15392 INCENP Homo sapiens Q9NQS7
Solution Sedimentation
17956729
Intra
BIRC5 O15392 XPO1 Homo sapiens O14980
Anti Bait CoIP
17099693
Intra
BIRC5 O15392 TARDBP Homo sapiens Q13148
Validated Y2H
32814053
Intra
BIRC5 O15392 TARDBP Homo sapiens Q13148
Y2H Array
32814053
Intra
BIRC5 O15392 TARDBP Homo sapiens Q13148
Y2H Pooling
32814053
Intra
BIRC5 O15392 AURKC Homo sapiens Q9UQB9
Y2H
21988832
Intra
BIRC5 O15392 AURKC Homo sapiens Q9UQB9
Anti Tag CoIP
27332895
Intra
BIRC5 O15392 CDK1 Homo sapiens P06493
Anti Bait CoIP
17681274
Intra
BIRC5 O15392 CDK1 Homo sapiens P06493
IF
17681274
Intra
BIRC5 O15392 HTT Homo sapiens P42858
Validated Y2H
32814053
Intra
BIRC5 O15392 HTT Homo sapiens P42858
Y2H Array
32814053
Intra
BIRC5 O15392 HTT Homo sapiens P42858
Y2H Pooling
32814053
Intra
BIRC5 O15392 DIABLO Homo sapiens Q9NR28
Pull Down
23251006
Intra
BIRC5 O15392 CDCA8 Homo sapiens Q53HL2
IF
21051298
Intra
BIRC5 O15392 CDCA8 Homo sapiens Q53HL2
Solution Sedimentation
17956729
Intra
BIRC5 O15392 CDCA8 Homo sapiens Q53HL2
X-Ray Diffraction
17956729
Intra
BIRC5 O15392 CDCA8 Homo sapiens Q53HL2
Y2H
20739936
Intra
BIRC5 O15392 CDCA8 Homo sapiens Q53HL2
Footprinting
17956729
Intra
BIRC5 O15392 CDCA8 Homo sapiens Q53HL2
PLA
21051298
Intra
BIRC5 O15392 CDCA8 Homo sapiens Q53HL2
GMS
17956729
Intra
BIRC5 O15392 CDCA8 Homo sapiens Q53HL2
Anti Tag CoIP
33961781
Intra
BIRC5 O15392 CDCA8 Homo sapiens Q53HL2
Anti Tag CoIP
28514442
Intra
BIRC5 O15392 AURKB Homo sapiens Q96GD4
Protein Kinase Assay
19357306
Intra
BIRC5 O15392 AURKB Homo sapiens Q96GD4
Anti Bait CoIP
24571573
Intra
BIRC5 O15392 AURKB Homo sapiens Q96GD4
Anti Bait CoIP
17099693
Intra
BIRC5 O15392 AURKB Homo sapiens Q96GD4
Anti Tag CoIP
27332895
Intra
BIRC5 O15392 LAMTOR5 Homo sapiens O43504
Y2H Array
32296183
Intra
BIRC5 O15392 LAMTOR5 Homo sapiens O43504
Y2H Prey Pooling
32296183
Intra
BIRC5 O15392 CCDC85B Homo sapiens Q15834
Validated Y2H
32296183
Intra
BIRC5 O15392 CCDC85B Homo sapiens Q15834
Y2H Prey Pooling
32296183
Intra
BIRC5 O15392 CCDC85B Homo sapiens Q15834
Y2H Array
32296183
Intra
BIRC5 O15392 OPTN Homo sapiens Q96CV9
Validated Y2H
32814053
Intra
BIRC5 O15392 OPTN Homo sapiens Q96CV9
Y2H Pooling
32814053
Intra
BIRC5 O15392 OPTN Homo sapiens Q96CV9
Y2H Array
32814053
Intra
BIRC5 O15392 APP Homo sapiens P05067
Validated Y2H
32814053
Intra
BIRC5 O15392 APP Homo sapiens P05067
Y2H Array
32814053
Intra
BIRC5 O15392 APP Homo sapiens P05067
Y2H Pooling
32814053
Intra
BIRC5 O15392 GAS2L3 Homo sapiens Q86XJ1
Anti Bait CoIP
24571573
Intra
BIRC5 O15392 BECN1 Homo sapiens Q14457
Anti Tag CoIP
20638385
Intra
BIRC5 O15392 BECN1 Homo sapiens Q14457
Anti Bait CoIP
20638385
Intra
BIRC5 O15392 SNCA Homo sapiens P37840
Validated Y2H
32814053
Intra
BIRC5 O15392 SNCA Homo sapiens P37840
Y2H Array
32814053
Intra
BIRC5 O15392 SNCA Homo sapiens P37840
Y2H Pooling
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant BIRC5 Proteins

製品番号 製品名 アクセッション番号 純度
HY-P7645 BIRC5 Protein, Human O15392-1 (M1-D142) ≥ 95%, as determined by reducing SDS-PAGE.

BIRC5 抗体

製品番号 製品名 アプリケーション 反応性
HY-P80352 Survivin/BIRC5 Antibody (YA045) WB, ICC/IF, IHC-P, FC Human, Mouse
HY-P80906 Survivin/BIRC5 Antibody (YA665) WB, IHC-P Human, Rat
HY-P83830 Survivin/BIRC5 Antibody (YA3527) WB, IHC-P, ICC/IF, FC, ELISA Human
HY-P83830A Survivin/BIRC5 Antibody (YA3527)(PBS only) WB, IHC-P, ICC/IF, FC, ELISA Human
HY-P85731 Survivin/BIRC5 Antibody (YA5423) WB, IHC-P, ICC/IF Human, Rat
HY-P86537 Survivin/BIRC5 Antibody (YA6229) WB, IHC-P, ICC/IF, IP, ELISA Human, Mouse, Rat

関連疾患

Diseases Alias
Adenocarcinoma

  • Adenocarcinomas

  • Adenoacanthoma Of Unspecified Site

  • Adenocarcinoid Of Unspecified Site

  • Adenocarcinoid Tumour Of Unspecified Site

  • Adenocarcinoma And Carcinoid Combined Of Unspecified Site

  • Adenocarcinoma Nos
Cervical Intraepithelial Neoplasia

  • CIN
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Laryngeal Squamous Cell Carcinoma

  • Epidermoid Carcinoma Of The Larynx

  • Squamous Cell Carcinoma Of Larynx

  • Squamous Cell Carcinoma Of The Larynx

  • Squamous Cell Carcinoma Of Head And Neck
Transitional Cell Carcinoma

  • Transitional Cell Neoplasm

  • Carcinoma, Transitional Cell

  • Transitional Carcinoma

  • Transitional Cell Tumor

  • Urothelial Cell Carcinoma

  • Carcinoma Transitional Cell

  • Transitional Cell Carcinoma Of Bladder
Ovarian Cancer

  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary
Bladder Cancer

  • Urinary Bladder Cancer

  • Bladder Carcinoma

  • Urinary Bladder Carcinoma

  • Bladder Neoplasm

  • Bladder Tumor

  • Cancer, Bladder

  • Malignant Neoplasm Of Urinary Bladder

  • Carcinoma Of Bladder

  • Bladder Cancer, Somatic

  • Tumor Of The Bladder

  • Carcinoma Of Urinary Bladder

  • Bladder Carcinoma Urinary

  • Cancer Of The Urinary Bladder

  • Cancer, Urinary Bladder

  • Malignant Bladder Neoplasm

  • Malignant Bladder Tumor

  • Neoplasm Of The Bladder

  • Neoplasm Of The Urinary Bladder

  • Tumor Of The Urinary Bladder

  • Urinary Bladder Neoplasm

  • BLC

  • Urothelial Carcinoma Of The Bladder

  • Bladder Tumors

  • Urinary Bladder Neoplasms

  • Bladder Cancer Nos

  • Vesical Cancer Nos

  • Malignant Neoplasm Of Bladder, Part Unspecified

  • Malignant Tumour Of Urinary Bladder

  • Primary Malignant Neoplasm Of Bladder
Adult Malignant Schwannoma

  • Adult Mpnst

  • Adult Neurofibrosarcoma
Severe Congenital Neutropenia

  • Congenital Neutropenia

  • Neutropenia, Severe Congenital

  • Congenital Agranulocytosis

  • Infantile Genetic Agranulocytosis

  • Kostmann Disease

  • Kostmann'S Agranulocytosis

  • Kostmann'S Syndrome

  • Severe Infantile Genetic Neutropenia
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Pancreatic Cancer

  • Pancreatic Carcinoma

  • Carcinoma Of Pancreas

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Cancer Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Pancreatic Adenocarcinoma

  • Adenocarcinoma Of The Pancreas

  • Adenocarcinoma Of Pancreas

  • Pancreas Adenocarcinoma

  • Malignant Exocrine Neoplasm

  • Primary Pancreatic Adenocarcinoma

  • Adenocarcinoma Of Islet Cell Of Pancreas

  • Islet Cell Adenocarcinoma Of Unspecified Site

  • Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site
Hepatoblastoma
Burkitt Lymphoma

  • Burkitt'S Lymphoma

  • BL

  • Burkitt Lymphoma, Somatic

  • Burkitt Lymphoma/Leukaemia

  • Burkitt'S Tumor

  • Burkitt'S Tumor Or Lymphoma

  • Malignant Lymphoma, Burkitt'S Type

  • Small Non-Cleaved Cell Lymphoma, Burkitt'S Type

  • Small Non-Cleaved Cell Lymphoma

  • Burkitt Tumor

  • Burkitts Lymphoma

  • Lymphoma, Small Noncleaved-Cell

  • Burkitt Tumour

  • Diffuse Small Noncleaved Malignant Burkitt Lymphoma

  • Malignant Burkitt Lymphoma

  • “Burkitt-Like” Lymphoma

  • Undifferentiated Burkitt Lymphoma

  • Small Noncleaved Cell Burkitt Lymphoma
Cystadenocarcinoma
Endometrial Cancer

  • Endometrial Carcinoma

  • Endometrial Neoplasm

  • Malignant Neoplasm Of Endometrium

  • Endometrioid Carcinoma

  • Endometrial Neoplasms

  • Carcinoma, Endometrioid

  • Endometrial Cancer, Familial

  • Endometrial Carcinoma, Somatic

  • Endometrial Cancer, Susceptibility To

  • Endometrial Ca

  • Malignant Endometrial Neoplasm

  • Neoplasm Of Endometrium

  • Primary Malignant Neoplasm Of Endometrium

  • Tumor Of Endometrium

  • Carcinoma Of The Endometrium

  • Endometrioid Carcinoma Of Female Reproductive System

  • ENDMC

  • Carcinoma Endometrioid

  • Endometrial Cancers

  • Cancer, Endometrial

  • Uterine Corpus Cancer
Hepatocellular Carcinoma

  • Liver Cancer

  • Primary Liver Cancer

  • HCC

  • Hepatoma

  • Malignant Neoplasm Of Liver

  • Liver Neoplasms

  • Cancer, Hepatocellular

  • Liver Cell Carcinoma

  • Lcc

  • Hepatoblastoma, Somatic

  • Hepatic Cancer

  • Primary Malignant Neoplasm Of Liver

  • Rare Tumor Of Liver And Intrahepatic Biliary Tract

  • Hepatocellular Carcinoma, Somatic

  • Hepatocellular Carcinoma, Childhood Type, Somatic

  • Hepatocellular Cancer, Somatic

  • Ca Liver - Primary

  • Hepatic Neoplasm

  • Malignant Hepato-Biliary Neoplasm

  • Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

  • Malignant Neoplasm Of Liver, Primary

  • Malignant Tumor Of Liver

  • Neoplasm Of Liver

  • Non-Resectable Primary Hepatic Malignant Neoplasm

  • Resectable Malignant Neoplasm Of Liver

  • Resectable Malignant Neoplasm Of The Liver

  • Primary Liver Carcinoma

  • Primary Malignant Liver Neoplasm

  • Primary Cancer Of Liver

  • Primary Tumor Of The Liver

  • Rare Tumor Of Liver And Ibt

  • Hepatocellular Cancer

  • Neoplasm Of The Liver

  • Carcinoma, Hepatocellular

  • Hepatomas

  • Liver Neoplasm

  • Liver Carcinoma

  • Liver And Intrahepatic Biliary Tract Carcinoma

  • Malignant Hepatobiliary Neoplasm

  • Adult Primary Hepatocellular Carcinoma

  • Hepatoblastoma

  • Carcinoma Of Liver

  • Malignant Liver Tumour

  • Malignant Hepatic Tumour
Acute Leukemia

  • Stem Cell Leukaemia

  • Stem Cell Leukemia

  • Acute Leukemias

  • Acute Undifferentiated Leukemia

  • Undifferentiated Leukemia

  • Acute Leukaemia Of Unspecified Cell Type Without Mention Of Remission

  • Blast Cell Leukaemia

  • Blast Leukaemia

  • Blastic Leukaemia

  • Undifferentiated Leukaemia
Renal Cell Carcinoma, Nonpapillary

  • Renal Cell Carcinoma

  • RCC

  • Nonpapillary Renal Cell Carcinoma

  • Clear Cell Renal Cell Carcinoma

  • Hypernephroma

  • Adenocarcinoma Of Kidney

  • Renal Carcinoma, Chromophobe, Somatic

  • Clear Cell Carcinoma Of Kidney

  • Clear-Cell Metastatic Renal Cell Carcinoma

  • Clear Cell Renal Carcinoma

  • Renal Cell Carcinoma, Somatic

  • Conventional Renal Cell Carcinoma

  • Conventional Renal Cell Carcinoma

  • Renal Clear Cell Carcinoma

  • Ccrcc

  • Hereditary Clear Cell Renal Cell Carcinoma

  • Carcinoma, Renal Cell

  • Renal Cell Carcinoma, Clear Cell, Somatic

  • Renal Cell Carcinoma, Clear Cell

  • Clear Cell Kidney Carcinoma

  • Clear Cell Rcc

  • Cystic-Multilocular Variant

  • Clear Cell Renal Cell Adenocarcinoma

  • Hereditary Clear Cell Renal Cell Adenocarcinoma

  • Common Renal Cell Carcinoma

  • Crcc

  • Renal Cell Carcinoma Non-Papillary

  • Carcinoma Renal Cell

  • Renal Cell Cancer

  • Carcinoma, Renal Cell, Nonpapillary
Benign Meningioma

  • Meningioma, Benign
Gastric Cancer

  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach
Prostate Cancer

  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer
Cervical Cancer

  • Cervical Cancer, Somatic

  • Neoplasm Of Uterine Cervix

  • Cervix Cancer

  • Uterine Cervical Neoplasm

  • Cervical Neoplasm

  • Cervix Uteri Cancer

  • Tumor Of The Cervix Uteri

  • CERCA

  • Uterine Cervical Cancer

  • Neoplasms Cervical

  • Uterine Cervical Neoplasms

  • Cervical Cancers

  • Cancer, Cervical, Somatic

  • Malignant Tumor Of Cervix

  • Cervix Carcinoma
Glioblastoma

  • Glioblastoma Multiforme

  • Gbm

  • Adult Glioblastoma Multiforme

  • Grade Iv Adult Astrocytic Tumor

  • Primary Glioblastoma Multiforme

  • Spongioblastoma Multiforme

  • Adult Glioblastoma

  • Primary Glioblastoma
Squamous Cell Carcinoma

  • Epidermoid Carcinoma

  • Squamous Cell Cancer

  • Carcinoma, Squamous Cell

  • Squamous Cell Skin Cancer

  • Malignant Squamous Cell Tumor

  • Squamous Carcinoma

  • Squamous Cell Epithelioma

  • Carcinoma Squamous Cell

  • Neoplasms, Squamous Cell

  • Squamous Cell Carcinoma - Category

  • Malignant Squamous Cell Neoplasm

  • Squamous Cell Carcinoma Of Skin
Rectum Cancer

  • Malignant Neoplasm Of Rectum

  • Rectal Cancer

  • Cancer Of Rectum

  • Carcinoma Of Rectum

  • Carcinoma Of The Rectum

  • Malignant Rectal Tumor

  • Malignant Rectum Tumor

  • Malignant Tumor Of Rectum

  • Rectal Carcinoma

  • Rectal Cancers

  • Cancer, Rectal
B-Cell Lymphoma

  • Lymphoma, B-Cell

  • B-Cell Lymphomas

  • B-Cell Lymphocytic Neoplasm

  • Lymphoma B-Cell

  • B-Cell Lymphoma Nos
Myelodysplastic Syndrome

  • Myelodysplastic Syndromes

  • Myelodysplasia

  • MDS

  • Myelodysplastic Syndrome Included

  • Myelodysplastic Syndrome, Susceptibility To, Included

  • Myelodysplastic Syndrome, Somatic

  • Myelodysplastic Syndrome, Susceptibility To
Breast Cancer

  • Breast Carcinoma

  • Male Breast Cancer

  • Breast Cancer, Familial

  • Malignant Neoplasm Of Breast

  • Breast Cancer, Susceptibility To

  • Breast Cancer, Early-Onset

  • Malignant Tumor Of Breast

  • Carcinoma Of Male Breast

  • Breast Cancer, Invasive Ductal

  • Breast Cancer, Protection Against

  • Breast Cancer, Somatic

  • Breast Cancer, Male

  • Breast Cancer, Lobular, Somatic

  • Breast Tumor

  • Mammary Cancer

  • Mammary Tumor

  • Malignant Neoplasm Of Male Breast

  • Mammary Carcinoma

  • Male Breast Carcinoma

  • Familial Cancer Of Breast

  • Invasive Ductal Breast Carcinoma

  • Breast Cancer Susceptibility

  • Breast Cancer, Male, Susceptibility To

  • Breast Cancer, Early-Onset, Susceptibility To

  • Malignant Tumor Of The Breast

  • Mammary Neoplasm

  • Primary Breast Cancer

  • Neoplasm Of Male Breast

  • Carcinoma Of Breast

  • Breast Cancer In Men

  • Familial Breast Cancer

  • Cancer Of Breast

  • BC

  • Breast Cancer Familial

  • Breast Cancer Familial Male

  • Breast Cancer, Familial Male

  • Breast Male Carcinoma

  • Breast Neoplasms

  • Breast Neoplasms, Male

  • Mammary Tumors

  • Mammary Carcinomas

  • Cancer, Breast

  • Cancer, Breast, Susceptibility

  • Invasive Breast Ductal Carcinoma

  • Breast Neoplasm

  • Susceptibility To Breast Cancer

  • Mammary Neoplasms

  • Animal Mammary Neoplasms

  • Primary Malignant Neoplasm Of Breast

  • Infiltrating Ductal Carcinoma Of Breast

  • Infiltrating Duct Carcinoma Of Unspecified Site

  • Infiltrating Ductular Carcinoma Of Unspecified Site

  • Invasive Breast Carcinoma Of No Special Type

  • Microinvasive Carcinoma Of Breast

  • Carcinoma With Apocrine Differentiation
Gastrointestinal Carcinoma

  • Gastrointestinal Neoplasms
Primary Cutaneous T-Cell Non-Hodgkin Lymphoma

  • Cutaneous T-Cell Lymphoma

  • Cutaneous T Cell Lymphoma

  • Lymphoma, T-Cell, Cutaneous

  • Ctcl

  • Lymphoma T-Cell Cutaneous
High Grade Glioma

  • Malignant Glioma

  • Glial Cell Tumor

  • Glioma, Malignant

  • Malignant Neuroglial Tumor

  • Neuroglial Tumor

  • Glioma

  • Malignant Gliomas
Urinary System Disease

  • Abnormality Of The Urinary System

  • Non-Neoplastic Urinary Tract Disease

  • Urinary Tract Disease

  • Urinary Tract Diseases

  • Urinary Tract Anomaly

  • Urologic Diseases

  • Non-Neoplastic Urinary System Disorder

  • Congenital Malformation Of The Urinary System
Leukemia, Chronic Myeloid

  • Chronic Myeloid Leukemia

  • Chronic Myelogenous Leukemia

  • CML

  • Chronic Granulocytic Leukemia

  • Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib

  • Chronic Myeloid Leukaemia

  • Chronic Granulocytic Leukaemia

  • Chronic Myelogenous Leukaemia

  • Myeloid Leukemia, Chronic

  • Leukemia, Chronic Myelogenous

  • Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic

  • Cml - Chronic Myelogenous Leukemia

  • Cgl

  • Chronic Myelocytic Leukemia

  • Leukemia, Chronic Myeloid, Atypical

  • ACML

  • Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative

  • Myeloid Leukemia Chronic

  • Leukemia, Myeloid, Chronic

  • Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative

  • Cml- [Chronic Myeloid Leukaemia]

  • Cgl - [Chronic Granulocytic Leukaemia]

  • Chronic Myelocytic Leukaemia
Melanoma

  • Malignant Melanoma

  • Cutaneous Melanoma

  • Naevocarcinoma

  • Malignant Melanomas
T-Cell Acute Lymphoblastic Leukemia

  • T-Cell Leukemia

  • Acute T Cell Leukemia

  • Precursor T Lymphoblastic Leukemia

  • Precursor T-Lymphoblastic Lymphoma/Leukemia

  • T Acute Lymphoblastic Leukemia

  • T-Cell Acute Lymphocytic Leukaemia

  • T-Cell Lymphoblastic Leukemia/Lymphoma

  • Leukemia T-Cell

  • Leukemia, T-Cell

  • Leukemia, Acute, Lymphoblastic, T-Cell

  • Leukemia, T-Cell Acute Lymphoblastic

  • Leukemia, Acute T-Cell

  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

  • Precursor T-Cell Lymphoblastic Lymphoma

  • Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Brain Cancer

  • Adult Brain Tumor

  • Malignant Neoplasm Of Brain

  • Brain Neoplasms

  • Brain Neoplasm

  • Neoplasm Of Brain

  • Primary Malignant Neoplasm Of Brain

  • Brain Tumors

  • Adult Malignant Brain Neoplasm

  • Brain Neoplasm, Adult

  • Bt - Brain Tumour

  • Malignant Brain Tumour

  • Malignant Primary Brain Neoplasm

  • Malignant Primary Brain Tumor

  • Malignant Tumor Of Adult Brain

  • Malignant Tumor Of Brain

  • Primary Brain Neoplasm

  • Primary Brain Tumor

  • Tumor Of The Brain

  • Brain Tumor, Adult

  • Brain Tumor Primary

  • Malignant Primary Brain Tumors

  • Primary Brain Tumors

  • Cancer, Brain

  • Brain Tumor, Primary
Squamous Cell Carcinoma, Head And Neck

  • Squamous Cell Carcinoma Of The Head And Neck

  • HNSCC

  • Head And Neck Squamous Cell Carcinoma

  • Squamous Cell Carcinoma Of Lip

  • Squamous Cell Carcinoma, Head And Neck, Somatic

  • Carcinoma Of The Head And Neck

  • Squamous Cell Carcinomas Of Head And Neck

  • Scchn

  • Squamous Cell Carcinoma Of The Hypopharynx

  • Squamous Cell Carcinoma Of The Oropharynx

  • Squamous Cell Carcinoma Of Salivary Glands

  • Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses

  • Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses

  • Squamous Cell Carcinoma Of The Oral Cavity

  • Squamous Cell Carcinoma Of The Lip

  • Carcinoma, Squamous Cell Of Head And Neck

  • Lip Squamous Cell Carcinoma

  • Carcinoma, Squamous Cell, Head And Neck

  • Salivary Gland Squamous Cell Carcinoma

  • Cancer Of Head And Neck

  • Squamous Cell Carcinoma Of Oropharynx Nos
Lung Cancer Susceptibility 3

  • Lung Adenocarcinoma

  • Adenocarcinoma Of Lung

  • LNCR3

  • Adenocarcinoma Of Lung, Susceptibility To

  • Bronchogenic Lung Adenocarcinoma

  • Nonsmall Cell Adenocarcinoma

  • Adenocarcinoma Lung

  • Lung Adenocarcinomas

  • Non-Small Cell Adenocarcinoma
Basal Cell Carcinoma

  • Basal Cell Cancer

  • Basal Cell Neoplasm

  • Basal Cell Carcinoma Of Skin

  • Malignant Basal Cell Tumor

  • Basal Cell Tumor

  • Epithelioma Basal Cell

  • Malignant Basal Cell Neoplasm

  • Rodent Ulcer

  • Carcinoma Basal Cell

  • Neoplasms, Basal Cell

  • Basal Cell Carcinomas

  • Experimental Organism Basal Cell Carcinoma

  • Nodulo-Ulcerative Basal Cell Carcinoma

  • Basalioma

  • Basal Cell Epithelioma Of Skin

  • Bcc - [Basal Cell Carcinoma] Of Skin

  • Rodent Ulcer Of Skin

  • Rodent Ulcer Of Unspecified Site

  • Basal Cell Epithelioma Of Unspecified Site
Lymphoma, Non-Hodgkin, Familial

  • Non-Hodgkin Lymphoma

  • Lymphoma, Non-Hodgkin

  • NHL

  • Lymphoma, Non-Hodgkin, Somatic

  • Lymphoma, Follicular, Somatic

  • Familial Non-Hodgkin Lymphoma

  • Lymphoma Non-Hodgkins

  • Follicular Lymphoma, Somatic

  • Lymphosarcoma

  • Non-Hodgkins Lymphoma
Hematologic Cancer

  • Hematologic Neoplasm

  • Hematologic Neoplasms

  • Hematologic Malignancies

  • Blood Cancer

  • Hematologic Malignancy

  • Hematological Tumors

  • Hematopoietic And Lymphoid System Tumor

  • Hematopoietic Cancer

  • Hematopoietic Neoplasm

  • Hematopoietic Tumors

  • Malignant Hematopoietic Neoplasm

  • Liquid Tumor

  • Hematopoietic Neoplasms
Uterine Adnexa Cancer
Neuroblastoma

  • Nb

  • Neuroblastoma, Susceptibility To

  • Neuroblastomas

  • Central Neuroblastoma
Medulloblastoma

  • MDB

  • Cpnet

  • Localized Primitive Neuroectodermal Tumor

  • Classic Medulloblastoma

  • Medulloblastoma Predisposition Syndrome

  • Medulloblastoma, Somatic

  • Brain Medulloblastoma

  • Cns Pnet

  • Infratentorial Primitive Neuroectodermal Tumor

  • Neuroectodermal Tumors, Primitive

  • Medulloblastomas

  • Desmoplastic Medulloblastoma

  • Medulloblastoma, With Extensive Nodularity

  • Medulloblastoma Of Unspecified Site

  • Medullomyoblastoma Of Unspecified Site
Myeloma, Multiple

  • Multiple Myeloma

  • Plasma Cell Myeloma

  • Kahler Disease

  • Myelomatosis

  • Medullary Plasmacytoma

  • Multiple Myeloma, Resistance To

  • Myeloma

  • Plasma Cell Dyscrasia

  • Kahler'S Disease

  • Multiple Myeloma, Susceptibility To

  • Myeloma - Multiple

  • Kahler-Bozzolo Disease

  • Plasma Cell Myelomas

  • MM

  • Plasma Cell Neoplasm

  • Primary Systemic Amyloidosis

  • Primary Amyloidosis

  • Immunoglobulin Deposition Disease

  • Plasmacytic Myeloma

  • Multiple Myelomata

  • Multiple Myeloma Nos

  • Multiple Myeloma Without Mention Of Remission

  • Monostotic Plasma Cell Myeloma

  • Mm - [Multiple Myeloma]
Leukemia, Chronic Lymphocytic

  • Chronic Lymphocytic Leukemia

  • B-Cell Chronic Lymphocytic Leukemia

  • CLL

  • B-Cell Chronic Lymphoid Leukemia

  • Chronic Lymphatic Leukemia

  • Chronic Lymphocytic Leukaemia

  • Lymphoplasmacytic Leukemia

  • Small Lymphocytic Lymphoma

  • Leukemia, Chronic Lymphatic

  • B-Cell Chronic Lymphocytic Leukaemia

  • Chronic Lymphatic Leukaemia

  • Lymphoplasmacytic Leukaemia

  • B Cell Chronic Lymphocytic Leukemia

  • Chronic B-Cell Lymphocytic Leukemia

  • Leukemia, Lymphocytic, Chronic

  • B-Cll

  • Chronic Lymphoid Leukemia

  • Leukemia Lymphocytic Chronic

  • Lymphoma Small Lymphocytic

  • Leukemia, Lymphocytic, Chronic, B-Cell
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-124447 BTYNB 98.0% Unkown
HY-173025 Nurr1 agonist 12 Agonist 99.62% Unkown
HY-175352 Nurr1 agonist 14 99.42% Unkown
HY-RS01513 BIRC5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17902 Birc5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24371 Birc5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus BIRC5 VGNC VGNC:26501
Canis familiaris BIRC5 VGNC VGNC:38461
Rattus norvegicus BIRC5 RGD RGD:70499
Mus musculus BIRC5 MGD MGI:1203517
Others BIRC5 NCBI