MI-217
Based on 1 Customer Validation
MI-217 is a potent SIRT3 inhibitor. MI-217 induces MDA-MB-231 apoptosis. MI-217 can be used in the study of breast cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.52%
- CAS 番号: 301202-06-2
- 分子式: C10H12N4O2S
- 分子量:252.29
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保管条件:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Vero | IC50 |
0.5 mM
Compound: 2h
|
Compound tested on intracellular parasites Toxoplasma gondii in vero cells after 24 h
Compound tested on intracellular parasites Toxoplasma gondii in vero cells after 24 h
|
[PMID: 15863319] |
| Vero | IC50 |
2.5 mM
Compound: 2h
|
Compound tested on vero cells infected with Toxoplasma gondii after 24 h
Compound tested on vero cells infected with Toxoplasma gondii after 24 h
|
[PMID: 15863319] |
化学情報
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CAS 番号 301202-06-2
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性状 Solid
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分子量 252.29
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分子式 C10H12N4O2S
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Color Light yellow to yellow
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SMILES
S=C(N/N=C/C1=CC=C([N+]([O-])=O)C=C1)NCC
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (396.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (265 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9637 mL | 19.8185 mL | 39.6369 mL | 99.0923 mL |
| 5 mM | 0.7927 mL | 3.9637 mL | 7.9274 mL | 19.8185 mL | |
| 10 mM | 0.3964 mL | 1.9818 mL | 3.9637 mL | 9.9092 mL | |
| 15 mM | 0.2642 mL | 1.3212 mL | 2.6425 mL | 6.6062 mL | |
| 20 mM | 0.1982 mL | 0.9909 mL | 1.9818 mL | 4.9546 mL | |
| 25 mM | 0.1585 mL | 0.7927 mL | 1.5855 mL | 3.9637 mL | |
| 30 mM | 0.1321 mL | 0.6606 mL | 1.3212 mL | 3.3031 mL | |
| 40 mM | 0.0991 mL | 0.4955 mL | 0.9909 mL | 2.4773 mL | |
| 50 mM | 0.0793 mL | 0.3964 mL | 0.7927 mL | 1.9818 mL | |
| 60 mM | 0.0661 mL | 0.3303 mL | 0.6606 mL | 1.6515 mL | |
| 80 mM | 0.0495 mL | 0.2477 mL | 0.4955 mL | 1.2387 mL | |
| 100 mM | 0.0396 mL | 0.1982 mL | 0.3964 mL | 0.9909 mL |