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製品番号: HY-163460

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MS8535

MS8535 is a SPIN1 selective inhibitor, with an IC₅₀ of 0.2 μM.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 3060589-97-8
分子式: C₂₈H₃₈N₆O₂
分子量:490.64

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (240 KB)

MS8535 構造式

CAS 番号: 3060589-97-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

MS8535 is a SPIN1 selective inhibitor, with an IC₅₀ of 0.2 μM^[1].

Epigenetic Reader Domain アイソフォーム固有の製品をすべて表示 :

体外実験

MS8535 (compound 18, 0-10 μM) concentration dependently blocks the interactions between SPIN1 and histone H3 in U2OS cells with an EC₅₀ of 1.1 ± 0.3 μM (n = 2)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

MS8535 (compound 18, 5 mg/kg, ip) is well tolerated by the treated mice and no clinical signs are observed in the PK study^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 3060589-97-8
分子量 490.64
分子式 C₂₈H₃₈N₆O₂
SMILES

COC1=CC2=C(C=C1OCCCN3CC4=C(C3)C=CC=C4)N=C(NCCN(C)C)N=C2N5CCCC5
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.