Panaxytriol
Panaxytriol is an active component of ginseng. Panaxytriol inhibits the nuclear translocation of NF-κB, thereby reducing the production of pro-inflammatory factors (such as TNF-α, IL-1β, IL-6) and nitric oxide (NO) induced by LPS (HY-D1056). Panaxytriol upregulates CYP3A4 by activating the nuclear receptor PXR/CAR. Panaxytriol improves motor dysfunction in a mouse model of brain inflammation. Panaxytriol can be used in the research of neurodegenerative diseases (such as Alzheimer's disease).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 87005-03-6
- 分子式: C17H26O3
- 分子量:278.39
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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NF-κB |
IL-1β |
IL-6 |
CYP3A4 |
化学情報
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CAS 番号 87005-03-6
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分子量 278.39
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分子式 C17H26O3
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SMILES
CCCCCCC[C@@H](O)[C@H](O)CC#CC#C[C@H](O)C=C
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Yan J, et al. Panaxytriol upregulates CYP3A4 expression through the interaction between nuclear regulators and DNA response elements. J Ethnopharmacol. 2023 Jun 28;310:116398. [Content Brief]
[2]. Hiramatsu G, et al. Panaxytriol Inhibits Lipopolysaccharide-Induced Microglia Activation in Brain Inflammation in Vivo. Biol Pharm Bull. 2021;44(7):1024-1028. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Panaxytriol 関連分類
HY-W709413 関連分類
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