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Petosemtamab

(別名: MCLA-158)
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Based on 1 Customer Validation

Petosemtamab (MCLA-158) is an anti- EGFR (Kd: 0.22 nM) and anti-LGR5 (Kd: 0.86 nM) monoclonal antibody (mAb). Petosemtamab leads to EGFR signaling blockade and receptor degradation in LGR5+ cancer cells. Petosemtamab can be used in the research of solid tumors, such as head and neck squamous cell carcinoma (HNSCC), metastatic colorectal cancer (CRC).

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度 : 99.90%
  • CAS 番号: 2213450-26-9
  • 分子量:145.5 kDa
  • 保管条件:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Petosemtamab
  • Experimental Validation Results for Petosemtamab
  • Experimental Validation Results for Petosemtamab
  • Petosemtamab Chemical Structure
    Petosemtamab 構造式
CAS 番号: 2213450-26-9
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Other Forms of Petosemtamab:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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100 mg

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized EGFR Protein, Human (621a.a, CHO, His, HY-P7340) can bind Petosemtamab. The EC50 for this effect is 4.45 ng/mL.

  • 1/16

    Immobilized HY-P79308 Lgr5/GPR49 Protein, Human (CHO, hFc) can bind Petosemtamab. The EC50 for this effect is 85 ng/mL.

  • Petosemtamab Chemical Structure
    1/16
  • Petosemtamab
  • Immobilized EGFR Protein, Human (621a.a, CHO, His, HY-P7340) can bind Petosemtamab. The EC50 for this effect is 4.45 ng/mL.
  • Immobilized HY-P79308 Lgr5/GPR49 Protein, Human (CHO, hFc) can bind Petosemtamab. The EC50 for this effect is 85 ng/mL.