Pipercide
Based on 1 Customer Validation
Pipercide is an amide of piper nigrum fruits. Pipercide has larvicidal activity to mosquito. Pipercide acts on the nervous system and induces repetitive discharge on the central nerve cord. Pipercide can be used as an insecticide.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.59%
- CAS 番号: 54794-74-0
- 分子式: C22H29NO3
- 分子量:355.47
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>40 μM
Compound: 16
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Antiproliferative activity against human A549 cells after 3 days by SRB assay
Antiproliferative activity against human A549 cells after 3 days by SRB assay
|
[PMID: 25241925] |
| DU-145 | IC50 |
>40 μM
Compound: 16
|
Antiproliferative activity against human DU145 cells after 3 days by SRB assay
Antiproliferative activity against human DU145 cells after 3 days by SRB assay
|
[PMID: 25241925] |
| Hepatocyte | IC50 |
2.6 μM
Compound: 27, retrofractamide B
|
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cytotoxicity after 20 hrs by MTT assay relative to untreated control
Hepatoprotective activity in ddY mouse hepatocytes assessed as inhibition of D-galactosamine/TNFalpha-induced cytotoxicity after 20 hrs by MTT assay relative to untreated control
|
[PMID: 19775895] |
| HepG2 | IC50 |
3.7 μM
Compound: Pipercide
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Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate addition measured after 25 mins by liquid scintillation counting analysis
Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate addition measured after 25 mins by liquid scintillation counting analysis
|
[PMID: 23419736] |
| KB | IC50 |
>40 μM
Compound: 16
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Antiproliferative activity against human KB cells after 3 days by SRB assay
Antiproliferative activity against human KB cells after 3 days by SRB assay
|
[PMID: 25241925] |
| MCF7 | IC50 |
>40 μM
Compound: 16
|
Antiproliferative activity against human MCF7 cells after 3 days by SRB assay
Antiproliferative activity against human MCF7 cells after 3 days by SRB assay
|
[PMID: 25241925] |
| MDA-MB-231 | IC50 |
>40 μM
Compound: 16
|
Antiproliferative activity against human MDA-MB-231 cells after 3 days by SRB assay
Antiproliferative activity against human MDA-MB-231 cells after 3 days by SRB assay
|
[PMID: 25241925] |
| SK-BR-3 | IC50 |
>40 μM
Compound: 16
|
Antiproliferative activity against human SK-BR-3 cells after 3 days by SRB assay
Antiproliferative activity against human SK-BR-3 cells after 3 days by SRB assay
|
[PMID: 25241925] |
| WI-38 | IC50 |
2 μM
Compound: 4
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Induction of senescence in human WI-38 cells
Induction of senescence in human WI-38 cells
|
[PMID: 38436272] |
| ZR-75-1 | IC50 |
>40 μM
Compound: 16
|
Antiproliferative activity against human ZR-75-1 cells after 3 days by SRB assay
Antiproliferative activity against human ZR-75-1 cells after 3 days by SRB assay
|
[PMID: 25241925] |
化学情報
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CAS 番号 54794-74-0
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性状 Solid
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分子量 355.47
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分子式 C22H29NO3
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Color White to off-white
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SMILES
CC(C)CNC(/C=C/C=C/CCCC/C=C/C1=CC=C(OCO2)C2=C1)=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 25 mg/mL (70.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (264 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8132 mL | 14.0659 mL | 28.1318 mL | 70.3294 mL |
| 5 mM | 0.5626 mL | 2.8132 mL | 5.6264 mL | 14.0659 mL | |
| 10 mM | 0.2813 mL | 1.4066 mL | 2.8132 mL | 7.0329 mL | |
| 15 mM | 0.1875 mL | 0.9377 mL | 1.8755 mL | 4.6886 mL | |
| 20 mM | 0.1407 mL | 0.7033 mL | 1.4066 mL | 3.5165 mL | |
| 25 mM | 0.1125 mL | 0.5626 mL | 1.1253 mL | 2.8132 mL | |
| 30 mM | 0.0938 mL | 0.4689 mL | 0.9377 mL | 2.3443 mL | |
| 40 mM | 0.0703 mL | 0.3516 mL | 0.7033 mL | 1.7582 mL | |
| 50 mM | 0.0563 mL | 0.2813 mL | 0.5626 mL | 1.4066 mL | |
| 60 mM | 0.0469 mL | 0.2344 mL | 0.4689 mL | 1.1722 mL |