Satratoxin G
Based on 1 Customer Validation
Satratoxin G is a large cyclic mucor toxin. Satratoxin G induces apoptosis by activation of caspase .
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.5%
- CAS 番号: 53126-63-9
- 分子式: C29H36O10
- 分子量:544.59
-
保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Caspase アイソフォーム固有の製品をすべて表示
More
生物活性
製品説明
体外実験
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Pathogen-free female C57Bl/6 mice [2]
-
Dosage:500 μg/kg
-
Administration:intranasal instillation
-
Result:Up-regulated the proapoptotic genes Fas, FasL, p75NGFR, p53, Bax, caspase-3, and CAD.
Increased expression of mRNAs for the cytokines TNF-α, IL-1α, IL-1β, and IL-6 as well as the chemokine MIP-2.
化学情報
-
CAS 番号 53126-63-9
-
性状 Solid
-
分子量 544.59
-
分子式 C29H36O10
-
Color White to off-white
-
SMILES
CC1=C[C@]2([H])[C@]([C@]3(C)[C@@]4(OC4)[C@](C[C@H]3OC(/C=C\C=C\[C@@]5(C(O)C)[C@H](O)[C@@]6(C7O6)CCO5)=O)([H])O2)(COC7=O)CC1
-
Structure Classification
-
Initial Source
aflatoxin
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
-
データシート (279 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Nagase M, et al. Molecular mechanism of satratoxin-induced apoptosis in HL-60 cells: activation of caspase-8 and caspase-9 is involved in activation of caspase-3. Immunol Lett. 2002 Oct 21;84(1):23-7. [Content Brief]
[2]. Islam Z, et al. Satratoxin G from the black mold Stachybotrys chartarum evokes olfactory sensory neuron loss and inflammation in the murine nose and brain. Environ Health Perspect. 2006 Jul;114(7):1099-107. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)