STAT6-IN-7
Based on 1 Customer Validation
STAT6-IN-7 is a STAT6 inhibitor. STAT6-IN-7 exhibits an IC50 of 0.28 μM for inhibiting the binding of human STAT6/pIL-4Rα. STAT6-IN-7 can be used in the research of atopic dermatitis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.53%
- CAS 番号: 3033743-58-4
- 分子式: C36H33F3N8O4
- 分子量:698.69
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
生物活性
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STAT6 |
IL-4 |
STAT6-IN-7 (Compound 178) is a STAT6 inhibitor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3033743-58-4
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性状 Solid
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分子量 698.69
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分子式 C36H33F3N8O4
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Color White to off-white
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SMILES
O=C(C1=CC(NC(C2=CC(C(F)(F)F)=CC3=C2N(CCOC)C(C4=CC=C(N5C(N(C)N=C5C)=O)C=C4)=C3)=O)=CC=C1)NC6=NN(C7CC7)C=C6
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
DMSO : 100 mg/mL (143.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4312 mL | 7.1562 mL | 14.3125 mL | 35.7812 mL |
| 5 mM | 0.2862 mL | 1.4312 mL | 2.8625 mL | 7.1562 mL | |
| 10 mM | 0.1431 mL | 0.7156 mL | 1.4312 mL | 3.5781 mL | |
| 15 mM | 0.0954 mL | 0.4771 mL | 0.9542 mL | 2.3854 mL | |
| 20 mM | 0.0716 mL | 0.3578 mL | 0.7156 mL | 1.7891 mL | |
| 25 mM | 0.0572 mL | 0.2862 mL | 0.5725 mL | 1.4312 mL | |
| 30 mM | 0.0477 mL | 0.2385 mL | 0.4771 mL | 1.1927 mL | |
| 40 mM | 0.0358 mL | 0.1789 mL | 0.3578 mL | 0.8945 mL | |
| 50 mM | 0.0286 mL | 0.1431 mL | 0.2862 mL | 0.7156 mL | |
| 60 mM | 0.0239 mL | 0.1193 mL | 0.2385 mL | 0.5964 mL | |
| 80 mM | 0.0179 mL | 0.0895 mL | 0.1789 mL | 0.4473 mL | |
| 100 mM | 0.0143 mL | 0.0716 mL | 0.1431 mL | 0.3578 mL |