STF-1623
Based on 1 Customer Validation
STF-1623 is a highly potent ENPP1 inhibitor with an IC50 of 0.6 nM. STF-1623 inhibits ENPP1, activates tumor-specific STING signaling. STF-1623 blocks breast, pancreatic, colon, and brain cancer progression.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.90%
- CAS 番号: 2298391-60-1
- 分子式: C16H22N3O4P
- 分子量:351.34
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
IC50: 0.6 nM (ENPP1)[1]
化学情報
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CAS 番号 2298391-60-1
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性状 Oil
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分子量 351.34
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分子式 C16H22N3O4P
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Color Light yellow to yellow
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SMILES
O=P(O)(O)CCC1CCN(C=2N=CN=C3C(OC)=CC=CC32)CC1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (142.31 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8462 mL | 14.2312 mL | 28.4625 mL | 71.1561 mL |
| 5 mM | 0.5692 mL | 2.8462 mL | 5.6925 mL | 14.2312 mL | |
| 10 mM | 0.2846 mL | 1.4231 mL | 2.8462 mL | 7.1156 mL | |
| 15 mM | 0.1897 mL | 0.9487 mL | 1.8975 mL | 4.7437 mL | |
| 20 mM | 0.1423 mL | 0.7116 mL | 1.4231 mL | 3.5578 mL | |
| 25 mM | 0.1138 mL | 0.5692 mL | 1.1385 mL | 2.8462 mL | |
| 30 mM | 0.0949 mL | 0.4744 mL | 0.9487 mL | 2.3719 mL | |
| 40 mM | 0.0712 mL | 0.3558 mL | 0.7116 mL | 1.7789 mL | |
| 50 mM | 0.0569 mL | 0.2846 mL | 0.5692 mL | 1.4231 mL | |
| 60 mM | 0.0474 mL | 0.2372 mL | 0.4744 mL | 1.1859 mL | |
| 80 mM | 0.0356 mL | 0.1779 mL | 0.3558 mL | 0.8895 mL | |
| 100 mM | 0.0285 mL | 0.1423 mL | 0.2846 mL | 0.7116 mL |