SYS6010
SYS6010 is an antibody-drug conjugate (ADC) targeting epidermal growth factor receptor (EGFR), which is formed by conjugating the anti-EGFR humanized IgG1 monoclonal antibody Becotatug (HY-P990049) with the topoisomerase I inhibitor JS-1 (HY-178217) via a cleavable tetrapeptide linker. SYS6010 can be used in the research of advanced solid tumors such as non-small cell lung cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
SYS6010 undergoes endocytosis, and its linker is cleaved by proteases to release the payload, thereby exerting anticancer effects after binding to EGFR on the surface of tumor cells[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
SMILES
[SYS6010]
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
SYS6010 関連分類
HY-185832 関連分類
Powered by Bioz
- SYS6010
- SYS 6010
- SYS-6010
- Antibody-Drug Conjugates (ADCs)
- EGFR
- Topoisomerase
- EGFR wild-type nonsquamous non-small cell lung cancer
- advanced solid tumors
- EGFR-mutant nonsquamous non-small cell lung cancer
- anti-EGFR humanized IgG1 monoclonal antibody
- antibody drug conjugate
- advanced esophageal squamous cell carcinoma
- topoisomerase I inhibitor
- epidermal growth factor receptor
- non-small cell lung cancer
- Inhibitor
- inhibitor
- inhibit