Thalidomide-SH
Thalidomide-SH is an E3 ubiquitin ligase cereblon (CRBN) ligand that recruits cereblon protein. Thalidomide-SH is a Thalidomide (HY-14658) derivative. Thalidomide-SH can be linked to a target protein ligand via a linker to form a PROTAC, such as SIAIS056 (HY-180969).
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- CAS 番号: 2378582-97-7
- 分子式: C13H10N2O4S
- 分子量:290.29
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2378582-97-7
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分子量 290.29
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分子式 C13H10N2O4S
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SMILES
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3S)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)