Tirandamycin A
Tirandamycin A, an antibiotic, is a bacterial RNA polymerase inhibitor. Tirandamycin A has antiamoebic and antibacterial properties.
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- CAS 番号: 34429-70-4
- 分子式: C22H27NO7
- 分子量:417.45
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
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RNA Polymerase |
Amebae |
体外実験
A 60 μM treatment with Tirandamycin A results in a slightly stronger inhibition, demonstrating a 84.2% reduction in growth of Entamoeba histolytica HM-1:IMSS and 64.8% reduction in growth by Entamoeba histolytica Col. Tirandamycin A inhibits chain initiation and elongation of bacterial RNA polymerase without acting on mammalian polymerases[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 34429-70-4
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分子量 417.45
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分子式 C22H27NO7
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SMILES
O=C(/C1=C(O)\C=C\C(C)=C\[C@H]([C@@H]2[C@@H](C)[C@@]3([H])C([C@]4([H])O[C@]4(C)[C@@](O3)(C)O2)=O)C)NCC1=O
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Structure Classification
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Initial Source
Streptomyces flaveolus strain Tu 1240
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Avelina Espinosa, et al. Antiamoebic properties of the actinomycete metabolites echinomycin A and tirandamycin A. Parasitol Res. 2012 Dec;111(6):2473-7. [Content Brief]
[2]. H Hagenmaier, et al. Metabiolic products of microorganisms. Tirandamycin B(author's transl). Arch Microbiol. 1976 Aug;109(1-2):65-74. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Tirandamycin A 関連分類
HY-126406 関連分類
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