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Vanucizumab

(別名: Anti-Human VEGFA Recombinant Antibody; RO5520985)
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Based on 1 Customer Validation

Vanucizumab is a first-in-class, bispecific IgG1-like monoclonal antibody that simultaneously blocks VEGF-A and angiopoietin-2 (Ang-2) from interacting with their receptors. Vanucizumab has antiangiogenic and anticancer effects.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度: 95.12%
  • CAS 番号: 1448221-05-3
  • 分子量:146.89 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Vanucizumab
  • Experimental Validation Results for Vanucizumab
  • Experimental Validation Results for Vanucizumab
  • Experimental Validation Results for Vanucizumab
  • Vanucizumab Chemical Structure
    Vanucizumab 構造式
CAS 番号: 1448221-05-3
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Vanucizumab おすすめ製品:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa-lambda with half-IG VL-CH1/VH-CK crossover

  • 1/16

    Immobilized Human VEGFA, His Tag can bind Vanucizumab. The EC50 for this effect is 4.575 ng/mL.

  • 1/16

    Immobilized Human ANGPT2, His Tag can bind Vanucizumab. The EC50 for this effect is 78.70 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 HeLa cells with Vanucizumab (HY-P99330, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.

  • Vanucizumab Chemical Structure
    1/16
  • Vanucizumab
  • Immobilized Human VEGFA, His Tag can bind Vanucizumab. The EC50 for this effect is 4.575 ng/mL.
  • Immobilized Human ANGPT2, His Tag can bind Vanucizumab. The EC50 for this effect is 78.70 ng/mL.
  • Flow cytometric analysis of 1X106 HeLa cells with Vanucizumab (HY-P99330, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control.
  • IgG1-kappa-lambda with half-IG VL-CH1/VH-CK crossover