Ispinesib-d5
Based on 1 Customer Validation
Ispinesib-d5 (SB-715992-d5) is a deuterium labeled Ispinesib (HY-50759). Ispinesib is a specific inhibitor of kinesin spindle protein (KSP).
For research use only. We do not sell to patients.
- Purity: 99.43%
- Formula: C30H28D5ClN4O2
- Molecular Weight:522.09
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Kinesin Isoforms
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Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 336113-53-2
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Appearance Solid
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Molecular Weight 522.09
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Formula C30H28D5ClN4O2
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Color White to off-white
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SMILES
O=C1N(CC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C([C@@H](C(C)C)N(CCCN)C(C3=CC=C(C)C=C3)=O)=NC4=CC(Cl)=CC=C14
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Synonyms
SB-715992-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (191.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9154 mL | 9.5769 mL | 19.1538 mL | 47.8845 mL |
| 5 mM | 0.3831 mL | 1.9154 mL | 3.8308 mL | 9.5769 mL | |
| 10 mM | 0.1915 mL | 0.9577 mL | 1.9154 mL | 4.7884 mL | |
| 15 mM | 0.1277 mL | 0.6385 mL | 1.2769 mL | 3.1923 mL | |
| 20 mM | 0.0958 mL | 0.4788 mL | 0.9577 mL | 2.3942 mL | |
| 25 mM | 0.0766 mL | 0.3831 mL | 0.7662 mL | 1.9154 mL | |
| 30 mM | 0.0638 mL | 0.3192 mL | 0.6385 mL | 1.5961 mL | |
| 40 mM | 0.0479 mL | 0.2394 mL | 0.4788 mL | 1.1971 mL | |
| 50 mM | 0.0383 mL | 0.1915 mL | 0.3831 mL | 0.9577 mL | |
| 60 mM | 0.0319 mL | 0.1596 mL | 0.3192 mL | 0.7981 mL | |
| 80 mM | 0.0239 mL | 0.1197 mL | 0.2394 mL | 0.5986 mL | |
| 100 mM | 0.0192 mL | 0.0958 mL | 0.1915 mL | 0.4788 mL |