5-Fluoro-lenalidomide
5-Fluoro-lenalidomide is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. 5-Fluoro-lenalidomide can be linked to a target protein ligand via a linker to form a PROTAC.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1918158-58-3
- 화학식: C13H12FN3O3
- 분자량:277.26
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1918158-58-3
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분자량 277.26
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화학식 C13H12FN3O3
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SMILES
O=C1NC(=O)C(N2C(=O)C=3C=C(F)C=C(N)C3C2)CC1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)