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Cat. No.: HY-186055

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Antimalarial agent 58

Antimalarial agent 58 is a diaminoquinoline methanol compound with weak in vitro activity against Plasmodium falciparum strain D6, and no activity against Plasmodium falciparum strains W2, C235 and C2A.

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CAS No.: 1258387-05-1
화학식: C₁₈H₂₂F₆N₄O
분자량:424.38

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Antimalarial agent 58 Chemical Structure

CAS No.: 1258387-05-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
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Bioz

Biological Activity

제품 설명

All Parasite Isoforms :

In Vitro

Antimalarial agent 58 (Compound 308384) exhibits weak in vitro activity against Pf D6 with an IC₉₀ of 380 ng/mL and no measurable activity (IC₉₀ > 500 ng/mL) against Pf W2, Pf C235, and Pf C2A strains of Plasmodium falciparum^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1258387-05-1
분자량 424.38
화학식 C₁₈H₂₂F₆N₄O
SMILES

FC(F)(C1=CC(C(CNCCNCCCN)O)=C(C=CC=C2C(F)(F)F)C2=N1)F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Milner E, et al. Structure-activity relationships of 4-position diamine quinoline methanols as intermittent preventative treatment (IPT) against Plasmodium falciparum. J Med Chem. 2011;54(18):6277-6285. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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- In Vitro
Chemical Information
순도&문서
References

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Antimalarial agent 58

All Parasite Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Antimalarial agent 58 Related Classifications

HY-186055 Related Classifications