Butriptyline
Butriptyline (Butriptylene) is an orally active tricyclic antidepressant that slightly enhances central 5-HT effects. Butriptyline does not inhibit brain norepinephrine uptake. Butriptyline can be used for depression research.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 35941-65-2
- 화학식: C21H27N
- 분자량:293.45
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
All 5-HT Receptor Isoforms
More
Biological Activity
Butriptyline hydrochloride (2.5-30 mg/kg; i.p.; 10-15 day intervals) causes a dose dependent depression of the food reinforced responses and slightly depresses the avoidance reflex at the highest doses in male albino rats[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Female CFLP mice, monosodium glutamate (MSG)-induced obesity model[1]
-
Dosage:1000 mg/kg
-
Administration:In diet, 10 weeks
-
Result:Significantly lowered the body weight.
Chemical Information
-
CAS No. 35941-65-2
-
분자량 293.45
-
화학식 C21H27N
-
SMILES
CC(CN(C)C)CC1C2=CC=CC=C2CCC3=C1C=CC=C3
-
Synonyms
Butriptylene
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Pugsley TA, et al. Effect of butriptyline on the brain uptake mechanisms for noradrenaline and 5-hydroxytryptamine. J Pharm Pharmacol. 1974 Oct;26(10):778-8. [Content Brief]
[2]. Dulloo AG, et al. Screening of drugs for thermogenic anti-obesity properties: antidepressants. Ann Nutr Metab. 1987;31(2):69-80. [Content Brief]
[3]. Molinengo L, et al. The action of imipramine, amitriptyline, doxepin and butriptyline in an operant conditioning schedule. Psychopharmacologia. 1972;24(2):247-57. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Butriptyline Related Classifications
HY-A0175 Related Classifications
Powered by Bioz