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Cat. No.: HY-107331

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Chlorproguanil

Chlorproguanil is an antifolate with an IC₅₀ of 4.68 μM against Plasmodium falciparum female gamete formation. Chlorproguanil can be used for the research of malaria.

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CAS No.: 537-21-3
화학식: C₁₁H₁₅Cl₂N₅
분자량:288.18

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Chlorproguanil Chemical Structure

CAS No.: 537-21-3

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
- Clinical Trial
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Chlorproguanil is an antifolate with an IC₅₀ of 4.68 μM against Plasmodium falciparum female gamete formation. Chlorproguanil can be used for the research of malaria^[1].

All Parasite Isoforms :

In Vitro

Chlorproguanil (0-25 μM; 48 h) inhibits P. falciparum stage V female gametocyte activation with a mean IC₅₀ of 4.68 μM following 48 h incubation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991			2011-05	PHASE1

Chemical Information

CAS No. 537-21-3
분자량 288.18
화학식 C₁₁H₁₅Cl₂N₅
SMILES

ClC1=CC=C(C=C1Cl)NC(=N)NC(=N)NC(C)C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Miguel-Blanco C, et al. Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation. Antimicrob Agents Chemother. 2015;59(6):3298-305. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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