Drupacine
Drupacine is a natural product, that can be isolated from Cephalotaxus harringtonia. Drupacine shows nematotoxicity and anticancer activity.
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- CAS No.: 49686-57-9
- 화학식: C18H21NO5
- 분자량:331.36
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
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Biological Activity
Drupacine shows cytotoxic effect on HCT-116, with IC50 of 16.20 ± 3.44 μM[1].
Drupacine shows cytotoxic effect for Bursaphelenchus xylophilus with ED50 of 27.1?μg/mL, and for Meloidogyne incognita with ED50 of 76.3?μg/mL, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 49686-57-9
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분자량 331.36
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화학식 C18H21NO5
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SMILES
O[C@H]1[C@]2([H])[C@]34C[C@]1(O[C@](CN3CCC4)([H])C5=CC(OCO6)=C6C=C25)OC
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Li Y, et al. Preparation of Stereo-Divergent Compounds from the Natural Product Drupacine Based on Complexity-to-Diversity Strategy. Chem Biodivers. 2023 Jun;20(6):e202300263. [Content Brief]
[2]. Wen Y, et al. Nematotoxicity of drupacine and a Cephalotaxus alkaloid preparation against the plant-parasitic nematodes Meloidogyne incognita and Bursaphelenchus xylophilus. Pest Manag Sci. 2013 Sep;69(9):1026-33. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Drupacine Related Classifications
HY-N3786 Related Classifications
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