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Cat. No.: HY-N20729

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Eucommin A

Eucommin A is a natural polyphenolic antioxidant. Eucommin A forms stable complexes with EGFR and MAPK8 via hydrogen bonding and hydrophobic interactions, and regulates osteoarthritis-related Autophagy. Eucommin A is applicable to research related to oxidative stress, such as osteoarthritis.

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CAS No.: 99633-12-2
화학식: C₂₇H₃₄O₁₂
분자량:550.56

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Eucommin A Chemical Structure

CAS No.: 99633-12-2

Amount: USD 0.00

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Use of MCE Products

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All EGFR Isoforms :

All p38 MAPK Isoforms :

In Vitro

Eucommin A binds tightly to purified human EGFR protein and human MAPK8 protein via multiple hydrogen bonds, with binding energies of -7.8 kcal/mol and -9.1 kcal/mol^[1].
Eucommin A is a polyphenolic component with in vitro antioxidant activity^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 99633-12-2
분자량 550.56
화학식 C₂₇H₃₄O₁₂
SMILES

O(C)C=1C=C([C@@H]2[C@@]3([C@@]([C@H](OC3)C4=CC(OC)=C(O)C=C4)(CO2)[H])[H])C=C(OC)C1O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Yage Zhang, et al. Bioinformatics-based identification of autophagy-related key genes in osteoarthritis and therapeutic potential analysis of Eucommin A[J]. Journal of Chinese Pharmaceutical Sciences, 2025, 34(9): 831-849.

[2]. Boubertakh H, et al. RP-UHPLC-ESI-QTOF-MSⁿ analyses, antioxidant, antimicrobial, analgesic activities and toxicity of Achillea ligustica All. Natural Product Research, 2025, 39(11): 3316-3321.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
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CAS No.:
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Purity:
수량:

Eucommin A

All EGFR Isoforms

All p38 MAPK Isoforms