FFN246
Based on 1 publication(s) in Google Scholar
FFN246 is a fluorescent, dual substrate of serotonin transporter (SERT) probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm. FFN246 can be used for labeling serotonergic neurons in mouse brain tissue through SERT-dependent accumulation.
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- Purity: 99.59%
- CAS No.: 2210244-83-8
- 화학식: C15H13FN2O
- 분자량:256.27
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) FFN246
MoreAll 5-HT Receptor Isoforms
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Biological Activity
FFN246 (20 μM, 30 mins) effectively traces serotonin uptake and packaging in the soma of serotonergic neurons[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2210244-83-8
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Appearance Solid
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분자량 256.27
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화학식 C15H13FN2O
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Color Light yellow to yellow
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SMILES
O=C1C2=CC(CCN)=CC=C2NC3=C1C(F)=CC=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Rep
2026 Jun 23;45(6):117387. PMID: 42250222
용액&용해도
DMSO : 16.67 mg/mL (65.05 mM; ultrasonic and warming and adjust pH to 1 with 1 M HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9021 mL | 19.5107 mL | 39.0213 mL | 97.5534 mL |
| 5 mM | 0.7804 mL | 3.9021 mL | 7.8043 mL | 19.5107 mL | |
| 10 mM | 0.3902 mL | 1.9511 mL | 3.9021 mL | 9.7553 mL | |
| 15 mM | 0.2601 mL | 1.3007 mL | 2.6014 mL | 6.5036 mL | |
| 20 mM | 0.1951 mL | 0.9755 mL | 1.9511 mL | 4.8777 mL | |
| 25 mM | 0.1561 mL | 0.7804 mL | 1.5609 mL | 3.9021 mL | |
| 30 mM | 0.1301 mL | 0.6504 mL | 1.3007 mL | 3.2518 mL | |
| 40 mM | 0.0976 mL | 0.4878 mL | 0.9755 mL | 2.4388 mL | |
| 50 mM | 0.0780 mL | 0.3902 mL | 0.7804 mL | 1.9511 mL | |
| 60 mM | 0.0650 mL | 0.3252 mL | 0.6504 mL | 1.6259 mL |
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