GQN-B37-E
GQN-B37-E is a potent selective binder and inhibitor of MCL-1. GQN-B37-E binds to the BH3-domain-binding pocket in MCL-1. GQN-B37-E exhibits binding affinity for MCL-1 at the submicromolar range (Ki = 0.6 μM) without apparent binding to BCL-2 or BCL-XL.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2982663-28-3
- 화학식: C29H23ClN4O4
- 분자량:526.97
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Mcl-1 0.6 μM (Ki) |
Chemical Information
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CAS No. 2982663-28-3
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분자량 526.97
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화학식 C29H23ClN4O4
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SMILES
O=C(O)[C@H](CC1=CNC2=CC=CC=C12)NC(/C=C/C3=CN(C4=CC=CC(Cl)=C4)N=C3C5=CC=C(O)C=C5)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)