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Cat. No.: HY-135779

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IU2-6

IU2-6 is a USP14 deubiquitinase inhibitor. IU2-6 inhibits deubiquitinating activity of proteasome-associated USP14, blocks substrate rescue from degradation, and enhances proteasomal activity. IU2-6 can be used for the research of neurodegeneration.

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CAS No.: 1356074-25-3
화학식: C₁₄H₁₇N₃S
분자량:259.37

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

IU2-6 Chemical Structure

CAS No.: 1356074-25-3

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

IC₅₀ & Target

^[1]

USP14

All Deubiquitinase Isoforms :

In Vitro

IU2-6 is a small molecule inhibitor of the USP14 deubiquitinase^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Neurotoxicity Study

Chemical Information

CAS No. 1356074-25-3
분자량 259.37
화학식 C₁₄H₁₇N₃S
SMILES

N=1C=NC(=C2C1SC3=C2CCCC3)N(C)C4CC4
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Schauer NJ, et al. Advances in Discovering Deubiquitinating Enzyme (DUB) Inhibitors. J Med Chem. 2020;63(6):2731-2750. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
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IU2-6

All Deubiquitinase Isoforms

Biological Activity

제품 설명

IC50 & Target

In Vitro

Chemical Information

순도&문서

References

Calculators

Help & FAQs

IU2-6 Related Classifications

HY-135779 Related Classifications

Bioz

Keywords

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