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Cat. No.: HY-118299

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JYL 1511

JYL 1511 is a partial agonist of vanilloid receptor VR1.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 623166-14-3
화학식: C₂₁H₂₉N₃O₃S₂
분자량:435.60

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

JYL 1511 Chemical Structure

CAS No.: 623166-14-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

JYL 1511 is a partial agonist of vanilloid receptor VR1^[1].

All TRP Channel Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	32.4 nM Compound: 3	Agonist activity at rat TRPV1 expressed in CHO cells by 45Ca2+ uptake assay Agonist activity at rat TRPV1 expressed in CHO cells by 45Ca2+ uptake assay	[PMID: 18406014]

In Vitro

JYL 1511 inhibits ^[3H]Resiniferatoxin binding to rat VR1 with a K_i of 50.4 nM^[1].
JYL 1511 inhibits Capsaicin induction of ⁴⁵Ca²⁺ uptake in CHO cells overexpressing rat VR1 (IC₅₀: 3.4 nM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 623166-14-3
분자량 435.60
화학식 C₂₁H₂₉N₃O₃S₂
SMILES

CS(=O)(NC1=CC=C(C=C1OC)CNC(NCC2=CC=C(C=C2)C(C)(C)C)=S)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang Y, et al. High-affinity partial agonists of the vanilloid receptor. Mol Pharmacol. 2003 Aug;64(2):325-33. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References

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JYL 1511

All TRP Channel Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

JYL 1511 Related Classifications

HY-118299 Related Classifications