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Cat. No.: HY-105479

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KF 18259

KF 18259 is a 5-HT3-receptor antagonist. KF 18259 inhibits the wrap-restraint stress-induced propulsive motility of the proximal and distal colon.

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CAS No.: 139094-48-7
화학식: C₂₂H₂₉ClN₂O₃
분자량:404.93

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

KF 18259 Chemical Structure

CAS No.: 139094-48-7

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- IC₅₀ & Target
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Biological Activity

제품 설명

KF 18259 is a 5-HT3-receptor antagonist. KF 18259 inhibits the wrap-restraint stress-induced propulsive motility of the proximal and distal colon^[1].

IC₅₀ & Target^[1]

5-HT₃ Receptor

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 139094-48-7
분자량 404.93
화학식 C₂₂H₂₉ClN₂O₃
SMILES

CN([C@@H](CC1)C2)[C@H]1C[C@@H]2OC(C(C3=CC=CC=C3N4CC(C)C)=CC4=O)=O.Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kishibayashi N, et al. Pharmacological properties of KF18259, a novel 5-HT3-receptor antagonist, in rats: inhibition of the distal colonic function. Jpn J Pharmacol. 1993 Dec;63(4):495-502. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
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KF 18259

All 5-HT Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

KF 18259 Related Classifications

HY-105479 Related Classifications