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Cat. No.: HY-W748000

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Kocurin

Name: Kocurin
Brand: MedChemExpress
SKU: HY-W748000
Availability: PreOrder

(Synonyms: PM181104; Baringolin)

Kocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against Gram-positive bacteria, but no activity against fungi and Gram-negative bacteria.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1374772-61-8
화학식: C₆₉H₆₆N₁₈O₁₃S₅
분자량:1515.70

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Kocurin Chemical Structure

CAS No.: 1374772-61-8

사이즈

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Antibiotic Isoforms :

In Vitro

Kocurin (24 h) inhibits S. aureus with MICs in the range of 0.008 to 2.048 μg/mL and an MIC₉₀ value of 0.064 μg/mL^[1].
Kocurin (24 h) inhibits S. epidermidis with MICs in the range of 0.008 to 1.024 μg/mL and an MIC₉₀ value of 0.128 μg/mL^[1].
Kocurin (24 h) inhibits VRE and VSE strains with MICs in the range of 0.004 to 1.024 μg/mL and an MIC₉₀ value of 0.016 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Kocurin (1.25-10 mg/kg; intravenous injection; single dose) has the 100% effective dose (ED₁₀₀) values of 2.5 and 5.0 mg/kg for MRSA, and an ED₁₀₀ value of 10.0 mg/kg for VRE in the BALB/c mouse septicemia model^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 1374772-61-8
분자량 1515.70
화학식 C₆₉H₆₆N₁₈O₁₃S₅
Synonyms

PM181104; Baringolin
Structure Classification
- Peptides
- Extract
Initial Source
- Marine natural products
- Sponge
- Microorganism
Micrococcus spp.
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (291 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mahajan G, et al. In vitro and in vivo activities of antibiotic PM181104. Antimicrob Agents Chemother. 2013 Nov;57(11):5315-9. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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