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Cat. No.: HY-14337

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MS 245

1 Cited Publications

고객리뷰

Based on 1 publication(s) in Google Scholar

MS 245 is an antagonist of the 5-HT₆ receptor wih an K_i value of 1.5 nM.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 263384-65-2
화학식: C₁₉H₂₂N₂O₃S
분자량:358.45

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

MS 245 Chemical Structure

CAS No.: 263384-65-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
Publications (1)
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Biological Activity

제품 설명

MS 245 is an antagonist of the 5-HT₆ receptor wih an K_i value of 1.5 nM^[1].

IC₅₀ & Target

5-HT₆ Receptor

1.5 nM (Ki)

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 263384-65-2
분자량 358.45
화학식 C₁₉H₂₂N₂O₃S
SMILES

O=S(N(C1=CC=C(OC)C=C21)C=C2CCN(C)C)(C3=CC=CC=C3)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Food Res Int

Disruption of the gut microbiota induces the LCA/TRPV6 signalling axis, impairing desmosome junctions in vitamin A-deficient rats. [Abstract]

2025 Dec;222(Pt 1):117656. PMID: 41267264

순도&문서

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Manik Pullagurla, et al. Modulation of the stimulus effects of (+)amphetamine by the 5-HT6 antagonist MS-245. Modulation of the stimulus effects of (+)amphetamine by the 5-HT6 antagonist MS-245. Pharmacol Biochem Behav. 2004 Jun;78(2):263-8. [Content Brief]

Calculators

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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- IC₅₀ & Target
Chemical Information
Publications (1)
순도&문서
References

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MS 245

Publications Citing Use of MedChemExpress (MCE) MS 245

All 5-HT Receptor Isoforms