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Cat. No.: HY-163460

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MS8535

MS8535 is a SPIN1 selective inhibitor, with an IC₅₀ of 0.2 μM.

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CAS No.: 3060589-97-8
화학식: C₂₈H₃₈N₆O₂
분자량:490.64

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (240 KB)

MS8535 Chemical Structure

CAS No.: 3060589-97-8

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Biological Activity
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- In Vivo
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Biological Activity

제품 설명

MS8535 is a SPIN1 selective inhibitor, with an IC₅₀ of 0.2 μM^[1].

All Epigenetic Reader Domain Isoforms :

In Vitro

MS8535 (compound 18, 0-10 μM) concentration dependently blocks the interactions between SPIN1 and histone H3 in U2OS cells with an EC₅₀ of 1.1 ± 0.3 μM (n = 2)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

MS8535 (compound 18, 5 mg/kg, ip) is well tolerated by the treated mice and no clinical signs are observed in the PK study^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3060589-97-8
분자량 490.64
화학식 C₂₈H₃₈N₆O₂
SMILES

COC1=CC2=C(C=C1OCCCN3CC4=C(C3)C=CC=C4)N=C(NCCN(C)C)N=C2N5CCCC5
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.