OPB-3206
OPB-3206 is a selective matrix metalloproteinase (MMP) inhibitor. OPB-3206 inhibits interstitial collagenase, gelatinase A (MMP-2), gelatinase B (MMP-9) and stromelysin with IC50 values of 7×10-7 M, 5×10-6 M, 5×10-7 M and 2×10-6 M, respectively. OPB-3206 reversibly binds to the zinc-binding region of MMPs, preventing the activation of MMP-9 and reducing extracellular matrix degradation to inhibit tumor lung metastasis. OPB-3206 is promising for research of lung metastasis of osteosarcoma.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 166245-54-1
- 화학식: C18H25N3O5
- 분자량:363.41
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
|
MMP-2 5 μM (IC50) |
MMP-9 0.5 μM (IC50) |
Chemical Information
-
CAS No. 166245-54-1
-
분자량 363.41
-
화학식 C18H25N3O5
-
SMILES
CON1C2=CC=CC=C2C[C@@H](C1=O)NC([C@H](CC(C)C)CC(NO)=O)=O
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
OPB-3206 Related Classifications
HY-171776 Related Classifications
Powered by Bioz