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Cat. No.: HY-146449

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PXYD4

PXYD4 is a ribosomal protein S1 (RpsA) antagonist with K_ds of 3.24 and 1.64 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb).

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CAS No.: 2712534-78-4
화학식: C₂₅H₂₁NO₅
분자량:415.44

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

PXYD4 Chemical Structure

CAS No.: 2712534-78-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

Kd: 3.24 μM (RpsA)^[1]

All Antibiotic Isoforms :

In Vitro

PXYD4 has high affinity for both RpsA-CTD (WT) and RpsA-CTD △438A (Mutant) with Kd values of 3.24 μM and 1.64 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2712534-78-4
분자량 415.44
화학식 C₂₅H₂₁NO₅
SMILES

CC1=CC=C(C=C1)CNC(COC2=CC3=C(C(O)=C2)C(C=C(O3)C4=CC=CC=C4)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yazhuang Dai, et al. Discovery and evaluation of new compounds targeting ribosomal protein S1 in antibiotic-resistant Mycobacterium Tuberculosis. Eur J Med Chem. 2020 Jun 15;196:112317. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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PXYD4

All Antibiotic Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

PXYD4 Related Classifications

HY-146449 Related Classifications